在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. MGST1 Recombinant Monoclonal Antibody

MGST1 Recombinant Monoclonal Antibody

  • 中文名稱：
    MGST1 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA906984A0HU
  • 規格：
    ￥1320
  • 圖片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate(30μg), HeLa whole cell lysate(30μg), A431 whole cell lysate(30μg), PC-3 whole cell lysate(30μg), U-251MG whole cell lysate(30μg), Mouse liver tissue lysate(30μg), Rat liver tissue lysate(30μg)
      All lanes: MGST1 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/40000 dilution
      Predicted band size: 18 kDa
      Observed band size: 18 kDa
      Exposure time：2min
    • IHC image of CSB-RA906984A0HU diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
    • IHC image of CSB-RA906984A0HU diluted at 1:100 and staining in paraffin-embedded human stomach tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
    • Overlay Peak curve showing 786-O cells stained with CSB-RA906984A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MGST1
  • 別名：
    Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I), MGST1, GST12 MGST
  • 反應種屬：
    Human, Mouse, Rat
  • 免疫原：
    A synthesized peptide from human MGST1 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    12H11
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:50-1:200
    FC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.
  • 基因功能參考文獻：
    1. High MGST1 expression is associated with Bendamustine-resistance in Mantle Cell Lymphoma. PMID: 29695404
    2. Significant association for germline variations only in the COX pathway (specifically in the antioxidant microsomal glutathione S-transferase 1 [MGST1] gene), with risk for Barrett's esophagus and the combined outcome of Barrett's esophagus and esophageal adenocarcinoma was found. PMID: 29713984
    3. This study provides the most comprehensive evaluation of inflammation-related germline variation in relation to risk of BE/OA and suggests that variants in MGST1 influence disease susceptibility. PMID: 27486097
    4. The MSGT1 displays a preexisting dynamic equilibrium between high- and low-activity forms. PMID: 28558199
    5. possibly marked variations in NB mitochondrial homeostasis, they also imply that the results of these earlier studies using NB cells are not transferable to other tumor and cell types that express MGST1 at high concentrations. PMID: 24486338
    6. Differential expression of SOD2, ALDH1A1, and MGST1 genes in the anterior lens capsules of patients with pseudoexfoliation syndrome suggest that diseased tissue appears to respond to the previously reported oxidative stress. PMID: 23805041
    7. The results suggest that MGST1 gene polymorphisms as one of environment gene may contribute to colorectal cancer risk in younger ages. PMID: 23314968
    8. MGST1 protects cells (and mitochondria) by both conjugation and glutathione peroxidase functions. A new protective mechanism against cisplatin is also indicated PMID: 20727966
    9. Polymorphisms in microsomal glutathione s transferase is associated with laryngeal cancer PMID: 12359356
    10. The results indicate that Sp1 is the protein mediating the basal transcription of MGST1 PMID: 12818425
    11. Genes encoding KU70, MGST1 and BIK show age-related mRNA expression levels in hematopoietic stem cells. PMID: 17714764
    12. As an addition to the high-density SNP (single-nucleotide polymorphism) maps of 12 glutathione S-transferase and related genes reported earlier, a SNP map of the microsomal glutathione S-transferase 1 (MGST1) gene is provided. PMID: 11587073

    顯示更多

    收起更多

  • 亞細胞定位：
    Microsome. Mitochondrion outer membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    MAPEG family
  • 組織特異性：
    Highly expressed in liver.
  • 數據庫鏈接：

    HGNC: 7061

    OMIM: 138330

    KEGG: hsa:4257

    STRING: 9606.ENSP00000010404

    UniGene: Hs.389700



主站蜘蛛池模板： 男人扒开女人双腿猛进免费视频| 久久国产精品无码hdav| 日韩精品一区国产偷窥在线| 日韩免费无码成人久久久久久片| 成年午夜无码av片在线观看| 欧美真人性做爰一二区| 国产成人精品亚洲日本在线| 日本久久久久久久做爰片日本| 99久久无色码中文字幕人妻蜜柚| av人摸人人人澡人人超碰手机版| 丰满人妻一区二区三区免费视频 | 国产精品乱码高清在线观看| 精品无码无人网站免费视频| 丰满岳乱妇在线观看中字 | 亚洲成av人片在www鸭子| 国产精品无码一本二本三本色 | 国产乱子伦精品免费女| 尤物蜜芽国产成人精品区| 永久免费无码av网站在线观看| 日本乱妇乱子视频网站-百度| 色综合天天无码网站| 国产又黄又湿无遮挡免费视频| 窝窝午夜看片| 天天躁日日躁狠狠躁超碰97| 伊人精品成人久久综合| 精品国产天堂综合一区在线| 国产sm调教折磨视频| 国产精品人成视频国模| 国产女主播白浆在线看| 女人扒开屁股桶爽30分钟| 国产免费丝袜调教视频| 国产无套水多在线观看| 日韩人妻无码免费视频一区二区三区 | 国产成人精品电影在线观看| 人禽无码视频在线观看| 天堂网www在线资源最新版| 大伊香蕉精品视频在线| 国产精品久久久久久久久动漫 | 免费国产高清毛不卡片基地| 国产综合色在线精品| 亚洲欧美精品伊人久久|