在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. EXOC3 Recombinant Monoclonal Antibody

EXOC3 Recombinant Monoclonal Antibody

  • 中文名稱：
    EXOC3 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA585966A0HU
  • 規格：
    ￥1320
  • 圖片：
    • IHC image of CSB-RA585966A0HU diluted at 1:100 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
    • IHC image of CSB-RA585966A0HU diluted at 1:100 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
    • Immunofluorescence staining of HepG2 cell with CSB-RA585966A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Overlay Peak curve showing Hela cells stained with CSB-RA585966A0HU (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100 for?10min. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated goat anti-rabbit IgG (H+L) at 1/200 dilution for 35min at 4℃.Control antibody (green line) was Rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    EXOC3
  • 別名：
    Exocyst complex component 3 (Exocyst complex component Sec6), EXOC3, SEC6 SEC6L1
  • 反應種屬：
    Human
  • 免疫原：
    A synthesized peptide from human EXOC3 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    11B2
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:200
    IF 1:50-1:200
    FC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
  • 基因功能參考文獻：
    1. Sec6 regulate Bcl-2 and Mcl-1 expressions but not Bcl-xl in malignant peripheral nerve sheath tumor cells. PMID: 26892009
    2. Sec6 regulates NF-kappaB transcriptional activity via the control of the phosphorylation of IkappaBalpha, p90RSK1, and ERK PMID: 26247921
    3. The study explores the role of the exocyst complex component Sec6/8 in genomic stability. PMID: 26283729
    4. Sec6 regulates cytoplasmic translocation of p27 through p27 phosphorylation at Thr157, thereby promoting p27 degradation in the cytoplasm via interaction with Jab1 and Siah1 and suppressing cell cycle progression. PMID: 24949832
    5. Data demonstrate that the expression of alpha-E-catenin is increased by Sec6 siRNAs, and E-cadherin and beta-catenin localize mainly at the cell-cell contact region in HSC3 cells, which were transfected with Sec6 siRNA. PMID: 22381337

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody. Golgi apparatus. Cell projection, neuron projection.
  • 蛋白家族：
    SEC6 family
  • 組織特異性：
    Expressed in epididymis (at protein level).
  • 數據庫鏈接：

    HGNC: 30378

    OMIM: 608186

    KEGG: hsa:11336

    STRING: 9606.ENSP00000323377

    UniGene: Hs.481464



主站蜘蛛池模板： 丝袜自慰一区二区三区| 四虎免费大片aⅴ入口| 少妇挑战三个黑人惨叫4p国语| 国产又色又爽又黄的在线观看视频| 无码少妇高潮浪潮av久久| 农村乱人伦一区二区| 久久久久成人精品无码| 亚洲天堂2017无码| 免费国产在线精品一区不卡| 曰批视频免费30分钟成人| 男女做爰真人视频直播| 中文天堂在线www最新版官网 | 无遮挡又爽又刺激的视频 | 美女视频黄又黄又免费| 无码精品人妻一区二区三区98| 欧美综合天天夜夜久久| 久久精品动漫一区二区三区| 国产精品综合一区二区三区 | 亚洲精品国产精品乱码不卡√| 女性女同性aⅴ免费观女性恋| 国内精品久久久久久久久电影网| 少妇人妻挤奶水中文视频毛片| 精品无码av一区二区三区不卡| 国产又粗又硬又大爽黄老大爷视| 夜色约爱网站| 欧美又黄又大又爽a片三年片| 久久国产欧美日韩精品| 免费无码av片在线观看动漫| 超薄丝袜足j好爽在线观看| 1000部夫妻午夜免费| 免费的很黄很污的视频| 日本少妇xxx做受| 果冻传媒18禁免费视频| 亚洲色欧美色2019在线| 内射人妻无套中出无码| aaa午夜级特黄日本大片| 最近的中文字幕在线看视频| 中文字幕在线观看亚洲日韩| 中文字幕aav| 又嫩又硬又黄又爽的视频| 精品少妇人妻av一区二区|