在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 重組抗體
  4. ERAL1 Recombinant Monoclonal Antibody

ERAL1 Recombinant Monoclonal Antibody

  • 中文名稱：
    ERAL1 Recombinant Monoclonal Antibody
  • 貨號：
    CSB-RA007759MA1HU
  • 規格：
    ￥1320
  • 圖片：
    • IHC image of CSB-RA007759MA1HU diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
  • 其他：

產品詳情

  • 產品描述：
    ERAL1 Recombinant Monoclonal Antibody（CSB-RA007759MA1HU）是一款針對線粒體核糖體組裝因子ERAL1靶點開發的高特異性抗體。ERAL1作為線粒體核糖體小亞基的伴侶蛋白，在維持線粒體RNA穩定性及核糖體組裝中發揮關鍵作用，其表達異常與能量代謝紊亂及細胞凋亡調控密切相關。本產品經嚴格驗證，可精準識別內源性ERAL1蛋白，適用于ELISA和免疫組化（IHC）等實驗，其中IHC推薦使用稀釋比例為1:50-1:200，實驗數據顯示其在多種組織樣本中呈現清晰的定位信號與低背景干擾。該抗體適用于探究線粒體功能調控機制、細胞代謝相關通路研究以及疾病模型中ERAL1表達水平變化的分析，為解析線粒體相關疾病的分子機制提供可靠工具。其穩定性和重復性已通過多批次質檢驗證，適用于基礎科研領域中對線粒體核糖體組裝、RNA加工及能量代謝過程的分子生物學研究。
  • Uniprot No.：
  • 基因名：
    ERAL1
  • 別名：
    CEGA antibody; Conserved ERA like GTPase antibody; Conserved ERA-like GTPase antibody; ERA antibody; Era (E. coli G protein homolog) like 1 antibody; Era G protein like 1 (E. coli) antibody; Era G protein like 1 antibody; ERA W antibody; ERA-like protein 1 antibody; ERA-W antibody; Eral1 antibody; ERAL1_HUMAN antibody; ERAL1A antibody; ERAW antibody; GTP binding protein era homolog antibody; GTPase Era antibody; GTPase Era; mitochondrial antibody; GTPase human homolog of E. coli essential cell cycle protein Era antibody; H-ERA antibody; HERA A antibody; hERA antibody; HERA B antibody; HERAA antibody; HERAB antibody; mitochondrial antibody
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human ERAL1 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    27A9
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.
  • 基因功能參考文獻：
    1. Three women from three different families presented with signs of PS, including deafness and ovarian dysgenesis. We employed exome sequencing and identified a homozygous missense mutation in the ERAL1 gene, c.707A > T. The mutation leads to a damaging p.Asn236Ile substitution that is likely to interfere with the GTP binding capacity of the ERAL1 protein. PMID: 28449065
    2. Data show that loss of ERAL1 leads to rapid decay of nascent 12S mt-rRNA, consistent with a role as a mitochondrial RNA chaperone. PMID: 20604745
  • 相關疾病：
    Perrault syndrome 6 (PRLTS6)
  • 亞細胞定位：
    Mitochondrion matrix. Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes on the matrix side on the mitochondrial inner membrane.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Era GTPase family
  • 數據庫鏈接：

    HGNC: 3424

    OMIM: 607435

    KEGG: hsa:26284

    STRING: 9606.ENSP00000254928

    UniGene: Hs.3426



主站蜘蛛池模板： 亚洲国产成人第一天堂| 精品无人码麻豆乱码1区2区| 玩肥熟老妇bbw视频| 西西人体44www大胆无码| 久久人妻av中文字幕| 久久中文精品无码中文字幕下载| 黑人粗大猛烈进出高潮视频| 熟女人妻一区二区三区免费看| 久热国产精品视频一区二区三区| 亚洲国产老鸭窝一区二区三区| 国产影片av级毛片特别刺激| 亚洲伊人成综合网2222| 风韵犹存丰满大屁股熟妇视频 | 野外做受三级视频| 老子影院午夜伦不卡无码| 99久热re在线精品视频| 伊人狠狠色丁香婷婷综合| 黄桃av无码免费一区二区三区| 日本免费一区二区三区四区五区| 亚洲精品乱码久久久久久日本麻豆| 国产乱子伦视频在线播放| 欧美freesex黑人又粗又大| 99久久久无码国产精品9| 亚洲国产成人精品无码区一本| 国产在线拍揄自揄视频导航| 国产影片av级毛片特别刺激| 亚洲精品日韩一区二区电影| 激情偷乱人伦小说视频在线| 久久精品一区二区免费播放| 中文字幕在线不卡精品视频99| 99日本精品永久免费久久| 亚洲精品国产第一区第二| 午夜寂寞少妇aaa片毛片| 久久久久高潮综合影院| 色无码av在线播放| 人人妻人人妻人人人人妻人人| 亚洲美女高清aⅴ视频免费| 无码专区 丝袜美腿 制服师生| 艳妇臀荡乳欲伦交换在线播放| 无套内内射视频网站| 天天爽夜夜爽人人爽一区二区|