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ALPG Recombinant Monoclonal Antibody

  • 中文名稱:
    ALPG重組抗體
  • 貨號:
    CSB-RA001633MA1HU
  • 規格:
    ¥1320
  • 圖片:
    • The Binding Activity of Human ALPG with Anti-ALPG Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPG (CSB-MP001633HU) at 2 μg/mL can bind Anti-ALPG recombinant antibody , the EC50 is 14.09-23.17 ng/mL.
    • The Binding Activity of Human ALPP with Anti-ALPP/ALPG Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPP (CSB-MP001632HU) at 2 μg/mL can bind Anti-ALPP/ALPG recombinant antibody. The EC50 is 4.478-5.236 ng/mL.
  • 其他:

產品詳情

  • 產品描述:
    CSB-RA001633MA1HU是針對ALPG(堿性磷酸酶胎盤型)的重組單克隆抗體,靶向ALPG蛋白的特定表位。ALPG(亦稱PLAP)屬于堿性磷酸酶家族,主要參與磷酸酯代謝,并在胎盤組織及某些腫瘤細胞中特異性高表達,其表達水平與生殖細胞腫瘤、卵巢癌等疾病的生物學行為相關。本抗體采用重組蛋白免疫技術制備,經ELISA平臺嚴格驗證,展現出高特異性和靈敏性,可與天然及重組ALPG蛋白穩定結合,且不同批次間性能高度一致。其應用場景涵蓋體外檢測實驗,包括但不限于ELISA法檢測細胞裂解液或血清樣本中ALPG的定量分析,適用于生殖生物學、腫瘤標志物篩選及疾病機制研究等領域。該產品經過重組蛋白親和純化,確保低內毒素及交叉反應性,為科研人員提供穩定可靠的工具,滿足蛋白質功能研究、疾病模型構建及生物標志物開發等需求,所有數據均通過標準化的質控流程驗證。
  • Uniprot No.:
  • 基因名:
  • 別名:
    ALPG Recombinant Monoclonal Antibody
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human ALPG protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    hIgG1
  • 純化方式:
    Affinity-chromatography
  • 克隆號:
    29A5
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Alkaline phosphatase that can hydrolyze various phosphate compounds.
  • 基因功能參考文獻:
    1. aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID: 23467613
    2. These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID: 16412386
    3. Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID: 17009260
  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    Alkaline phosphatase family
  • 組織特異性:
    Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.
  • 數據庫鏈接:

    HGNC: 441

    OMIM: 171810

    KEGG: hsa:251

    STRING: 9606.ENSP00000295453

    UniGene: Hs.333509



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