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vpx Antibody, Biotin conjugated

Rare Species
  • 中文名稱:
    vpx兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA356976LD01HLZ
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Human immunodeficiency virus type 2 subtype A vpx Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    vpx
  • 別名:
    vpxProtein Vpx antibody; Viral protein X antibody; X ORF protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human immunodeficiency virus type 2 subtype A
  • 免疫原:
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-112AA)
  • 免疫原種屬:
    Human immunodeficiency virus type 2 subtype A
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
  • 亞細胞定位:
    Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG.
  • 蛋白家族:
    Lentivirus VPX protein family


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