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  4. vpx Antibody, Biotin conjugated

vpx Antibody, Biotin conjugated

Rare Species
  • 中文名稱：
    vpx兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA356976LD01HLZ
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Human immunodeficiency virus type 2 subtype A vpx Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    vpx
  • 別名：
    vpxProtein Vpx antibody; Viral protein X antibody; X ORF protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human immunodeficiency virus type 2 subtype A
  • 免疫原：
    Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-112AA)
  • 免疫原種屬：
    Human immunodeficiency virus type 2 subtype A
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription.
  • 亞細胞定位：
    Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG.
  • 蛋白家族：
    Lentivirus VPX protein family


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