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  4. vacA Antibody, Biotin conjugated

vacA Antibody, Biotin conjugated

Rare Species
  • 中文名稱：
    vacA兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA345927LD01HUV
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Helicobacter pylori vacA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    vacA
  • 別名：
    vacA antibody; HP_0887 antibody; Vacuolating cytotoxin autotransporter [Cleaved into: Vacuolating cytotoxin; Vacuolating cytotoxin translocator] antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Helicobacter pylori
  • 免疫原：
    Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter protein (37-245AA)
  • 免疫原種屬：
    Helicobacter pylori
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Induces vacuolation of eukaryotic cells. Causes ulceration and gastric lesions.
  • 基因功能參考文獻：
    1. Helicobacter pylori VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway. PMID: 29238039
    2. The results indicate that cortactin is involved in the regulation of apoptosis induced by VacA in gastric cells. PMID: 26289258
    3. Genotype testing of vacA s- and m- region will be useful in screening susceptible individuals for duodenal ulcer development. PMID: 25063579
    4. These results suggested that cagA and vacA gene expression is upregulated in Helicobacter pylori, especially by host cell contact, and Fur has a role in the upregulation. PMID: 24020886
  • 亞細胞定位：
    [Vacuolating cytotoxin autotransporter]: Periplasm.; [Vacuolating cytotoxin]: Secreted. Cell surface.; [Vacuolating cytotoxin translocator]: Cell outer membrane; Multi-pass membrane protein.
  • 數據庫鏈接：

    KEGG: hpy:HP0887

    STRING: 85962.HP0887



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