在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

tar Antibody, Biotin conjugated

Rare Species
  • 中文名稱:
    tar兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA356999HD01ENV
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Escherichia coli tar Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    tar
  • 別名:
    tar antibody; cheM antibody; b1886 antibody; JW1875Methyl-accepting chemotaxis protein II antibody; MCP-II antibody; Aspartate chemoreceptor protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Escherichia coli
  • 免疫原:
    Recombinant Escherichia coli Methyl-accepting chemotaxis protein II protein (212-553AA)
  • 免疫原種屬:
    Escherichia coli
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for the attractant L-aspartate and related amino and dicarboxylic acids. Tar also mediates taxis to the attractant maltose via an interaction with the periplasmic maltose binding protein. Tar mediates taxis away from the repellents cobalt and nickel.; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation, the methyl groups are added by the methyltransferase CheR and removed by the methylesterase CheB.
  • 基因功能參考文獻:
    1. Thus, the proportion of polypeptide chain that is locally and presumably transiently disordered is a structural feature of cytoplasmic domain dynamics that varies with functional region and modification-induced signaling state. PMID: 27318193
    2. There is a differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues. PMID: 25445668
    3. the Tar(FO) modules demonstrate that trimerized signaling tips self-associate, bind CheA and CheW, and facilitate conversion of CheA to an active conformation. PMID: 25967982
    4. Residues at the cytoplasmic end of transmembrane helix 2 determine the signal output of the Tar chemoreceptor. PMID: 23495653
    5. Such inversion is enabled by opposing pH sensing by the two major chemoreceptors, Tar and Tsr, such that the relative strength of the response is modulated by adaptive receptor methylation. PMID: 23078189
    6. Here we report the overexpression system for aCB2 in Escherichia coli C43(DE3) facilitated by two fusion partners: Mistic and TarCF, a C-terminal fragment of the bacterial chemosensory transducer Tar at the C-terminal of the CB2 open reading frame region. PMID: 22406258
    7. characterization of structural features of carboxyl-terminal 40 residues of Tar; identifed carboxyl-terminal linker between receptor body and the pentapeptide is an unstructured, disordered segment that can serve as a flexible arm and enzyme tether PMID: 21858888
    8. Ligand specificity is determined by differentially arranged common ligand-binding residues in bacterial amino acid chemoreceptors Tsr and Tar PMID: 21979954
    9. Tar molecules with the cytoplasmic methylation and kinase control domains of Tsr still sensed phenol as an attractant. PMID: 21965561
    10. The cytoplasmic domains of Tar and Tsr receptors are close to each other near the trimer contact region at the cytoplasmic tip. PMID: 21174433
    11. These results with Tar-EnvZ hybrid receptor mutants suggest that intersubunit interactions in the HAMP linker normally mediate signal transduction through both subunits in a sensor dimer. PMID: 15316026
    12. mutations in the protein motifs of Tar significantly reduced the ability of the transmembrane domains to dimerize PMID: 15330757
    13. The tryptophan residues flanking the second transmembrane helix of Tar, especially Trp-209, are crucial in setting the baseline activity and ligand sensitivity of this chemoreceptor. PMID: 15667220
    14. assisted adaptational modification (methylation, demthylation and deamidation) in vitro of Trg chemorecptor PMID: 15916610
    15. polar localization of Tar fused to green fluorescent protein is influenced by its own amidation (methylation) state and the expression of another chemoreceptor (Tsr) PMID: 16267289
    16. Data show that Tar can be readily mutated to respond to new chemical signals, but that the overall change in specificity depends on the target compound. PMID: 16359703
    17. The pentapeptide linker in Tar is important for chemotaxis because of its role in adaptational modification. PMID: 16573695
    18. The fundamental mechanism of transmembrane signaling is conserved between homodimeric sensor kinases (with NarX) and chemoreceptors. PMID: 16707686
    19. Data suggest that Tar()-Tsr* suppression most likely occurs through compensatory changes in the conformation or dynamics of a mixed receptor signaling complex, presumably based on trimer-of-dimer interactions. PMID: 16751275
    20. The organization of these receptor/signaling complexes is determined by conserved interactions between the constituent chemotaxis proteins and may represent the active form in vivo. PMID: 16973743
    21. A mutational analysis of Tar residues 505-548 reveals that the more of this region is deleted, the less sensitive Tar is to inhibition by aspartate. PMID: 19053273

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell inner membrane; Multi-pass membrane protein. Note=Found predominantly at cell poles.
  • 數據庫鏈接:


主站蜘蛛池模板: 精品久久一区二区乱码| 无码av高潮抽搐流白浆| 狠狠色丁香久久婷婷综合图片| 看国产黄大片在线观看| 欧美自拍亚洲综合丝袜| 亚洲の无码国产の无码步美| 韩国美女视频黄是免费| 无码中文人妻在线三区| 欧美日本特级婬片视频| 国产日韩在线视看第一页| www国产成人免费观看视频| 国产成人精品久久一区二区三区 | 国产欧美一区二区三区免费视频 | 18禁黄污无遮挡无码网站| 五十路熟妇高熟无码视频| 性猛交ⅹxxx富婆视频| 国产在线一区二区av视频| 亚洲成αv人片在线观看| 乌克兰少妇xxxx做受野外| 国产精品久久久久久久久动漫| 玩弄放荡人妇系列av在线网站| 成人看片黄a免费看| 免费无码毛片一区二区三区a片| 欧美成人一区二免费视频软件| 久久久免费精品re6| 亚洲精品久久yy5099| 亚洲精品无码av中文字幕| 国产av一区最新精品| 国内精品九九久久久精品| 成人黄网站高清免费视频| 亚洲aⅴ男人的天堂在线观看| 天堂资源中文网| 色欲天天天综合网| 少妇无码av无码专区| 色综合欧美在线视频区| 强迫大乳人妻中文字幕| 人人狠狠综合久久亚洲爱咲 | 免费人成视频x8x8入口| 久久久综合九色综合鬼色| 日本又黄又爽gif动态图| 极品少妇xxxx|