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sulA Antibody, HRP conjugated

Rare Species
  • 中文名稱:
    sulA兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA365383LB01ENV
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Escherichia coli sulA Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    sulA
  • 別名:
    sulA antibody; sfiA antibody; b0958 antibody; JW0941 antibody; Cell division inhibitor SulA antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Escherichia coli
  • 免疫原:
    Recombinant Escherichia coli Cell division inhibitor SulA protein (1-169AA)
  • 免疫原種屬:
    Escherichia coli
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU).
  • 基因功能參考文獻:
    1. In current work the recovery of division process of Escherichia coli cells after division arrest due to expression of SOS-response protein SulA was studied. Data indicate that cells are able to rapidly restore normal division; also nucleoid occlusion seems to be the main septum positioning mechanism during the process. PMID: 30188109
    2. results indicate existence of a SulA-dependent pathway of high-pressure-induced cell filamentation and suggest involvement of the SOS response, and particularly of SulA, in high-pressure-mediated cell death in strains which are compromised in Lon function PMID: 15748989
    3. Results found that the binding of SulA to FtsZ is necessary but not sufficient for inhibition of FtsZ polymerization. PMID: 18245292
  • 蛋白家族:
    SulA family
  • 數據庫鏈接:


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