在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

pstS1 Antibody, FITC conjugated

Rare Species
  • 中文名稱:
    pstS1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA14919C0Rb
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Mycobacterium tuberculosis pstS1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    pstS1
  • 別名:
    pstS1 antibody; phoS1 antibody; Rv0934 antibody; MTCY08D9.05c antibody; Phosphate-binding protein PstS 1 antibody; PBP 1 antibody; PhoS1 antibody; PstS-1 antibody; 38-kDa glycolipoprotein antibody; 38-kDa lipoprotein antibody; P38 antibody; Antigen Ag78 antibody; Protein antigen B antibody; Pab antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Mycobacterium tuberculosis
  • 免疫原:
    Recombinant Mycobacterium tuberculosis Phosphate-binding protein PstS 1 protein (24-373AA)
  • 免疫原種屬:
    Mycobacterium tuberculosis
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Functions in inorganic phosphate uptake, although probably not the main uptake protein under phosphate starvation. Binds phosphate; probably able to bind both H(2)PO(4)(-) and HPO(4)(2-). Part of the ABC transporter complex PstSACB involved in phosphate import.; A host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse. Requires both host TLR1 and TLR2 as coreceptors to elicit host response in mouse (TLR6 may also play a role) neither CD14 or CD36 function as accessory receptors. Protein purified from culture filtrate induces host (human) monocytes to produce TNF-alpha, IL-6 and IL-12 p40 (IL12B) via ERK1/2 (MAPK3 and MAPK1) and p38 MAPK pathways; MEK inhibitors U0126 and PD98059 and p38 inhibitor SB203580 block most cytokine production. Host ERK1/2 and p38 MAPK activation is mediated mainly by TLR2, but also partially by TLR4, and unlike the case for lipoprotein LpqH the protein moiety of PstS1 seems to be the antigenic agent. Greater activation of ERK1/2 and p38 MAPK is seen in patients with active pulmonary tuberculosis than in tuberculin-negative patients. Induces apoptosis when incubated with human monocyte-derived macrophages via TLR2. Protein purified from culture filtrate acts via TLR2 and TLR4 to induce host macrophage (shown for mouse) endoplasmic reticulum stress-mediated apoptosis via MAPK (at least JNK), C-C motif chemokine 2 (MCP-1, Ccl2) and ZC3H12 endoribonucleases (MCPIP, Zc3h12). Functions as an adhesin, binds to human and mouse macrophages via mannose residues, binds to the mouse macrophage mannose receptor (possibly Mrc1) and mediates bacterial phagocytosis.
  • 基因功能參考文獻:
    1. The interaction of PstS-1 coated beads with the mannose receptor was confirmed by confocal colocalization studies that showed high Pearson and Manders's colocalization coefficients. PMID: 25359607
    2. pstS1 polymorphisms of Mycobacterium tuberculosis strains may reflect ongoing immune evasion. PMID: 23849889
    3. Data indicate that the modulation of Natural killer (NK) cells by PstS-1 is mediated via monocytes. PMID: 23036052
  • 亞細胞定位:
    Cell membrane; Lipid-anchor. Cell surface. Secreted, cell wall. Secreted.
  • 蛋白家族:
    PstS family
  • 數據庫鏈接:

    KEGG: mtu:Rv0934

    STRING: 83332.Rv0934



主站蜘蛛池模板: 国产亚洲欧美另类一区二区| 天天综合爱天天综合色| 伊人久久精品无码二区麻豆 | 免费特级黄毛片| 久久国产精品精品国产色婷婷| 18禁止进入1000部高潮网站| 无码av岛国片在线播放| 国产精品久久精品第一页| 国产精品毛片无遮挡高清| 人妻夜夜爽天天爽| 99久久无码一区人妻a片蜜| 黄网站成人片免费视频| 又色又爽又黄又无遮挡的网站| 麻豆成人精品国产免费| 国产精品vr专区| 亚洲精品第一国产综合精品| 亚洲区小说区激情区图片区| 欧美大片欧美激情性色a∨在线| 国产精品亚亚洲欧关中字幕| 亚洲一区精品二人人爽久久| 亚洲欧洲日韩国内高清| 国产三级aⅴ在在线观看| 人人爽人人片人人片av| 亚洲欧美国产毛片在线| 欧洲人免费视频网站在线| 蜜桃av麻豆av果冻传媒| 男女猛烈无遮挡免费视频| 又色又爽又黄的吃奶视频免费观看| 国产日产亚洲系列最新美使用方法 | 福利视频在线播放| 久久人人97超碰超国产| 老熟妇乱子伦牲交视频| 亚洲国产精品久久久久爰色欲| 呻吟国产av久久一区二区| 精品无码成人久久久久久| 亚洲多毛妓女毛茸茸的| 国产乱人伦偷精品视频免下载| 春药玩弄少妇高潮吼叫| 亚洲一区二区三区国产精品无码| 国精无码欧精品亚洲一区| 婷婷色香合缴缴情av第三区|