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  4. oprF Antibody
  • 中文名稱：
    oprF兔多克隆抗體
  • 貨號：
    CSB-PA318417LA01EZX
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: oprF antibody at 5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 39.3 kDa
      Observed band size: 44 kDa
  • 其他：

產品詳情

  • 產品描述：

    The OprF polyclonal antibody is a rabbit antibody that specifically recognizes Pseudomonas aeruginosa OprF protein. Its immunogen is the recombinant Pseudomonas aeruginosa OprF protein (25-350aa). It has been validated for use in ELISA and WB assays. The antibody has been purified using protein G and has a purity level of over 95%.

    OprF is one of the major porins in the outer membrane of P. aeruginosa, participating in the uptake of nutrients and antibiotics, as well as in the efflux of toxins and metabolic waste products. It has also been implicated in virulence and pathogenesis in P. aeruginosa.

  • 產品名稱：
    Rabbit anti-Pseudomonas aeruginosa oprF Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    oprF
  • 別名：
    oprF antibody; PA1777 antibody; Outer membrane porin F antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Pseudomonas aeruginosa
  • 免疫原：
    Recombinant Pseudomonas aeruginosa Outer membrane porin F protein (25-350AA)
  • 免疫原種屬：
    Pseudomonas aeruginosa
  • 標記方式：
    Non-conjugated

    本頁面中的產品，oprF Antibody (CSB-PA318417LA01EZX)，的標記方式是Non-conjugated。對于oprF Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA318417LB01EZX oprF Antibody, HRP conjugated ELISA
    FITC CSB-PA318417LC01EZX oprF Antibody, FITC conjugated
    Biotin CSB-PA318417LD01EZX oprF Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium.
  • 基因功能參考文獻：
    1. OprF (an outer membrane porin, highly conserved in the Pseudomonas) binds human C3b. PMID: 25964476
    2. LecB binds to the outer membrane protein OprF PMID: 23056489
    3. oprF transcription was increased in response to low NaCl or high sucrose concentrations, and this induced transcription was strongly impaired in the absence of SigX. PMID: 22685281
    4. Prevention of disulfide bond formation in OprF increases its pore-forming activity. PMID: 20978537
    5. This is the first study showing a link between OprF, PQS synthesis, T3SS, and virulence factor production PMID: 21189321
    6. Data show that the recombinant plasmid pIRES-tPA-OprF-MyD88 has been successfully constructed and tPA-OprF and MyD88 protein can be highly expressed in transfected cells. PMID: 19257978
    7. findings suggest that OprF could adopt two alternative conformations in the outer membrane and that folding is thermoregulated PMID: 15528532
    8. findings demonstrate that interferon-gamma binds to an outer membrane protein in Pseudomonas aeruginosa, OprF, resulting in the expression of a quorum-sensing dependent virulence determinant, the PA-I lectin PMID: 16051797
    9. analysis of OprF from Pseudomonas aeruginosa PMID: 16397890
    10. OprF exists in two different conformations PMID: 16595653
    11. analysis of Pseudomonas aeruginosa porin OprF PMID: 16617058
    12. Major outer membrane protein F (OprF) is identified as a protein with important functions; mutant Pseudomonas aeruginosa deficient in OprF negates the antibacterial role of host neutrophil elastase both in vitro and in a pneumonia model. PMID: 18802098

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  • 亞細胞定位：
    Cell outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    OmpA family
  • 數據庫鏈接：

    KEGG: pae:PA1777

    STRING: 208964.PA1777



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