在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. mutL Antibody, FITC conjugated

mutL Antibody, FITC conjugated

Rare Species
  • 中文名稱：
    mutL兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA543397HC01ENV
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Escherichia coli mutL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    mutL
  • 別名：
    mutL antibody; b4170 antibody; JW4128 antibody; DNA mismatch repair protein MutL antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli DNA mismatch repair protein MutL protein (1-615AA)
  • 免疫原種屬：
    Escherichia coli
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA.
  • 基因功能參考文獻：
    1. In this review, we describe biochemical, biophysical and structural analyses that have clarified how MutL aids at discriminating the newly synthesized strand from its template and marking it for removal. [review] PMID: 25701376
    2. study found the deletion or insertion of a single LA repeat did not compromise the structural integrity of the protein, nor did it affect MutS- or DNA-binding activity;it severely compromised ATP binding and engagement of the N-terminal domains; both essential activities for proper DNA mismatch repair PMID: 23916559
    3. MutL accumulates from the mismatch site toward strand discrimination site along the DNA. PMID: 22241777
    4. Evidence for ATP-dependent structural rearrangement of nuclease catalytic site in DNA mismatch repair endonuclease MutL PMID: 21953455
    5. C-terminal domain of MutL encompasses a bona fide DNA polymerase III beta-binding motif that mediates a weak, yet specific, interaction between the two proteins. PMID: 21050827
    6. The presence of phosphate minimizes further MutL oligomerization beyond a dimer PMID: 21793594
    7. Studies indicate that a stable MutL-ssDNA interaction is unlikely to occur at physiological salt. PMID: 21103398
    8. MutL homologues play a key role in determining biologic outcome by recruiting and/or activating effector proteins in response to lesion recognition by MutS. PMID: 19953589
    9. Data report the crystal structure of the Escherichia coli MutL C-terminal dimerization domain and the likelihood of its conservation among MutL homologs. PMID: 15470502
    10. revised model for the biological dimer, which has important implications for understanding the heterodimerization of eukaryotic MutL homologues, modeling the MutL holoenzyme and predicting protein-protein interaction sites PMID: 16024043
    11. MutL determines effective DNA homology in recombination processes PMID: 17502621
    12. An increase in mutL gene copies was also able to partially compensate the hypermutator phenotype of a mutS-defective E. coli derivative. PMID: 17825069
    13. Results suggest a mobile MutS-MutL complex in DNA mismatch repair signalling, that leaves the DNA mismatch prior to, or at the time of, activation of downstream effector molecules such as Vsr or MutH. PMID: 19474347

    顯示更多

    收起更多

  • 蛋白家族：
    DNA mismatch repair MutL/HexB family
  • 數據庫鏈接：


主站蜘蛛池模板： 牛和人交xxxx欧美| 全国最大成人网| 欧美熟妇另类久久久久久不卡| 国产熟妇勾子乱视频| 成人做受视频试看120秒| 成年无码动漫av片在线尤物网站 | 无码人妻在线一区二区三区免费 | 精品成人免费一区二区不卡| 日韩a片无码一区二区三区电影| 欧美午夜成人片在线观看| 四川少妇大战4黑人| 无码精品a∨在线观看无广告| 国产精品亚洲а∨天堂| 久久久噜噜噜www成人网| 无码人妻丰满熟妇啪啪网站| 色v99在线影院| 中文字幕人妻丝袜成熟乱| 国产suv精品一区二区69| 中文人妻无码一区二区三区信息| 国产99青草视频在线播放视 | 无码人妻一区二区三区线| 国产亚洲精久久久久久无码77777| 人妻少妇伦在线麻豆m电影| 国内极度色诱视频网站| 国产免费无遮挡吸奶头视频| 无码h肉在线观看免费一区| 92午夜福利少妇系列| 天天鲁一鲁摸一摸爽一爽| 未满十八18禁止免费无码网站| 国产超碰人人模人人爽人人喊| 久久精品水蜜桃av综合天堂| 国产午夜无码视频在线观看| 免费国产乱理伦片在线观看| 人妻无码专区一区二区三区| 久久婷婷五月综合色中文字幕| 亚洲人成电影网站色| 国产精品美女乱子伦高潮 | 自拍偷在线精品自拍偷无码专区| 无码一区18禁3d| 偷妻之寂寞难耐2中文字幕| 亚洲成a人v影院色老汉影院|