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  4. luxS Antibody, Biotin conjugated

luxS Antibody, Biotin conjugated

Rare Species
  • 中文名稱：
    luxS兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA541717HD01ENV
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Escherichia coli luxS Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    luxS
  • 別名：
    luxS antibody; ygaG antibody; b2687 antibody; JW2662 antibody; S-ribosylhomocysteine lyase antibody; EC 4.4.1.21 antibody; AI-2 synthesis protein antibody; Autoinducer-2 production protein LuxS antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Escherichia coli
  • 免疫原：
    Recombinant Escherichia coli S-ribosylhomocysteine lyase protein (2-171AA)
  • 免疫原種屬：
    Escherichia coli
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
  • 基因功能參考文獻：
    1. study demonstrated that luxS affects the expression of flagella and Stx2e toxin, 2 important STEC virulence factors PMID: 24848979
    2. LuxS contributes to virulence in avian pathogenic Escherichia coli O78:K80:H9. PMID: 23958403
    3. Proteomic profiling of luxS mutants showed only a few proteins were differentially expressed and those that were altered suggested a metabolic rather than communication role for the E. coli luxS gene product. PMID: 23651217
    4. Deletion of the luxS gene reduced the bacterial virulence by 31.5-fold in ducklings. PMID: 23046700
    5. Polyphosphate degradation in stationary phase triggers biofilm formation via LuxS quorum sensing system in Escherichia coli. PMID: 23226268
    6. Pfs and LuxS synthesize AI-2 in vitro from S-ribosylhomocysteine. PMID: 23236852
    7. luxS deletion significantly increases swimming motility and flagella synthesis in Escherichia coli K12. PMID: 20875395
    8. These data are consistent with the function of LuxS as an important metabolic enzyme but appear not to support the role of AI-2 as a true signal molecule for E. coli W3110 under the investigated conditions. PMID: 16321939
    9. The active form of LuxS contains a metal-bound water and a thiolate ion at Cys-83, consistent with the proposed roles of the metal ion (Lewis acid) and Cys-83 (general acid/base) during catalysis. PMID: 17014073

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  • 蛋白家族：
    LuxS family
  • 數據庫鏈接：


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