在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. gL Antibody

gL Antibody

Rare Species
  • 中文名稱：
    gL兔多克隆抗體
  • 貨號：
    CSB-PA515269LA01HWW
  • 規(guī)格：
    ￥440
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Human cytomegalovirus gL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    gL
  • 別名：
    gL antibody; UL115Envelope glycoprotein L antibody; gL antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human cytomegalovirus
  • 免疫原：
    Recombinant Human cytomegalovirus Envelope glycoprotein L protein (31-278AA)
  • 免疫原種屬：
    Human cytomegalovirus
  • 標記方式：
    Non-conjugated

    本頁面中的產品，gL Antibody (CSB-PA515269LA01HWW)，的標記方式是Non-conjugated。對于gL Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA515269LB01HWW gL Antibody, HRP conjugated ELISA
    FITC CSB-PA515269LC01HWW gL Antibody, FITC conjugated
    Biotin CSB-PA515269LD01HWW gL Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA. The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2.
  • 基因功能參考文獻：
    1. Here, the authors provide a 19 A reconstruction for the cytomegalovirus gHgLgO trimer and show that it binds with high affinity through the gO subunit to PDGFRalpha, which is expressed on fibroblasts but not on epithelial cells. PMID: 27573107
    2. The results show the importance of highly conserved peptide sites of human cytomegalovirus glycoprotein O (gO) for the formation of the gH/gL/gO complex. PMID: 27795411
    3. The majority of the mutant gH/gL complexes were unable to facilitate gB-mediated membrane fusion in transient-expression cell-cell fusion experiments. PMID: 26656708
    4. Pentamer harboring the UL128-Cys162Ser/gL-Cys144Ser mutations had impaired syncytia formation and reduced interference of HCMV entry into epithelial cells PMID: 25624487
    5. gO diversity may influence the pathogenesis of HCMV through effects on the assembly of the core versus tropism gH/gL complexes. PMID: 23804643
    6. Instead, gO promoted the export of gH/gL from the endoplasmic reticulum (ER) and the accumulation of gH/gL in the trans-Golgi network. PMID: 21880752
    7. Glycoprotein L is required for infection and cell-to-cell spread of virus. PMID: 21191007
    8. Data suggest that TR gO acts as a chaperone to promote ER export and the incorporation of gH/gL complexes into the HCMV envelope. PMID: 20032184
    9. Data suggest that gO acts as a molecular chaperone, increasing gH/gL ER export and incorporation into virions. PMID: 20032193
    10. Human cytomegalovirus glycoproteins gB and gH/gL mediate epithelial cell-cell fusion when expressed either in cis or in trans. PMID: 18815310

    顯示更多

    收起更多

  • 亞細胞定位：
    Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans-Golgi network.
  • 蛋白家族：
    Herpesviridae glycoprotein L family
  • 數據庫鏈接：

    KEGG: vg:3077416



主站蜘蛛池模板： 国产欧美另类久久精品蜜芽| 国产精品天天狠天天看| 99久久免费国产精品四虎| 精品精品国产理论在线观看| 一区二区三区乱码在线 | 欧洲| 人妻熟女 视频二区 视频一区| 男人扒开女人内裤强吻桶进去| 国内精品久久久久久久久电影网| 丁香婷婷综合久久来来去| 国产精品a久久777777| 67194熟妇在线直接进入| 国产精品午夜无码av天美传媒| 免费观看羞羞视频网站| 日韩乱码人妻无码中文字幕| 另类亚洲综合区图片区小说| 久久狼人大香伊蕉国产| 伊人久久大香线蕉综合中文字幕| 久久久国产精品| 欧美老熟妇牲交| 久久发布国产伦子伦精品| 免费无码又爽又刺激高潮软件| 国语自产拍精品香蕉在线播放 | 欧美成人午夜免费全部完| 天天躁夜夜踩很很踩2022| 国产 | 欧洲野花视频欧洲1| 国产精成人品日日拍夜夜| 国产成a人亚洲精v品无码性色| 伊伊综合在线视频无码| 5x性社区免费视频播| 欧美熟妇乱子伦xx视频| 最新中文乱码字字幕在线| av免费网址在线观看| 欧美巨大xxxx做受高清| 欧美国产精品久久久乱码| 精品国偷自产在线视频99| 两个人看的www免费视频中文| 色五月激情五月| 亚洲不乱码卡一卡二卡4卡5 | 日韩午夜理论片 中文字幕| 欧美性潮喷xxxxx免费视频看| 国产成人精品三级麻豆|