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deoD Antibody, Biotin conjugated

Rare Species
  • 中文名稱:
    deoD兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA18357D0Rb
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Escherichia coli deoD Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    deoD
  • 別名:
    deoD antibody; pup antibody; b4384 antibody; JW4347 antibody; Purine nucleoside phosphorylase DeoD-type antibody; PNP antibody; EC 2.4.2.1 antibody; Inosine phosphorylase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Escherichia coli
  • 免疫原:
    Recombinant Escherichia coli Purine nucleoside phosphorylase DeoD-type protein (2-239AA)
  • 免疫原種屬:
    Escherichia coli
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Acts on 6-amino and 6-oxopurines including deoxyinosine, deoxyguanosine, deoxyadenosine, adenosine, guanosine, and inosine. Does not act on xanthosine. May also catalyze a phosphate-dependent transfer of the pentose moiety from one purine base to another.
  • 基因功能參考文獻:
    1. These studies also indicate an important role of the phenyl ring of Phe159 for FRET in the wild-type purine nucleoside phosphorylase, which does not exist in the Ala159 mutant, and for the effective association of PNP with formycin A . PMID: 25754135
    2. Data suggest that in active sites of purine nucleoside phosphorylase complexed with phosphate and formycin A, recombinant enzyme exhibits unexpected binding site for phosphate and exhibits stoichiometry of two phosphate molecules per enzyme subunit. PMID: 22569248
    3. The deoD gene was cloned from Escherichia coli MG1665 & overexpressed in E. coli BL 21(DE3). PMID: 22113014
    4. in solution similar to the crystal, E. coli PNP is a hexameric molecule and previous suggestions for coexistence of two oligomeric forms are incorrect. PMID: 16751611
    5. Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) PMID: 17639373

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  • 蛋白家族:
    PNP/UDP phosphorylase family
  • 數據庫鏈接:


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