在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA)

  • 中文名稱:
    牛PPP2CA重組蛋白
  • 貨號:
    018559BO
  • 規格:
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; EC 3.1.3.16
  • 免疫原種屬:
    Bos taurus (Bovine)
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 應用說明:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 儲存條件:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Can dephosphorylate p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. Mediates dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint. Mediates dephosphorylation of MYC; promoting its ubiquitin-mediated proteolysis: interaction with AMBRA1 enhances interaction between PPP2CA and MYC. Mediates dephosphorylation of FOXO3; promoting its stabilization: interaction with AMBRA1 enhances interaction between PPP2CA and FOXO3.
  • 基因功能參考文獻:
    1. changes in PP2A activity due to methylation and tyrosine phosphorylation occur in sperm; these changes may play an important role in the regulation of sperm function PMID: 26569399
    2. The findings demonstrate an endothelial VEGF resistance mechanism conferred by palmitic acid, which comprises ceramide-induced, PP2A-mediated dephosphorylation of critical activation sites on enzymes central to vascular homeostasis and angiogenesis. PMID: 24606881
  • 亞細胞定位:
    Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole.
  • 蛋白家族:
    PPP phosphatase family, PP-1 subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲欧美乱综合图片区小说区| 女人色极品影院| 99热门精品一区二区三区无码| 免费无码成人av在线播| 免费无码成人av在线播放不卡| 国产精品久久久久影院色| 5858s亚洲色大成网站www| 国产成a人亚洲精品无码樱花| 精品国产综合成人亚洲区| 青草久久人人97超碰| 国产成人av无码永久免费一线天| 免费无码又爽又刺激高潮的app| 97久久综合亚洲色hezyo| 人妻中文字幕乱人伦在线| 亚洲国产精品久久久天堂麻豆宅男 | 国产精品久久精品第一页| 欧美顶级少妇作爱| 亚洲欧洲无码一区二区三区| 色欲天天婬色婬香综合网完整版| a级大胆欧美人体大胆666| 大地资源在线观看官网第三页| 日产精品一区二区| 国内偷自第一区二区三区| 亚洲中文字幕无码一去台湾| 国产午夜理论不卡在线观看| 久久久久久久综合狠狠综合| 国产成人av在线影院| 精品无码综合一区二区三区| 乱码午夜-极国产极内射| 久久人人爽av亚洲精品| 日韩中文亚洲欧美视频二| 无码无套少妇毛多18pxxxx| 国产亚洲人成a在线v网站| 拍国产乱人伦偷精品视频| 亚洲色欲色欲77777小说网站| 国产欧美成人一区二区a片| 巨爆乳无码视频在线观看| 成人无码a片一区二区三区免| 国产亚洲视频在线观看网址| 人妻熟女一区二区aⅴ千叶宁真| 琪琪女色窝窝777777|