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  4. ZNF408 Antibody, HRP conjugated

ZNF408 Antibody, HRP conjugated

  • 中文名稱：
    ZNF408兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào)：
    CSB-PA026728LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ZNF408 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZNF408
  • 別名：
    EVR6 antibody; PFM14 antibody; PR domain zinc finger protein 17 antibody; PRDM17 antibody; RP72 antibody; Zinc finger protein 408 antibody; ZN408_HUMAN antibody; ZNF408 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 408 protein (317-635AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in transcriptional regulation.
  • 基因功能參考文獻(xiàn)：
    1. This is the first study to report a group of patients with digenic familial exudative vitreoretinopathy (FEVR). In most affected eyes, the stage was more severe than stage 3. We speculate that the phenotype of FEVR is more severe in patients with digenic rather than monogenic variants of FEVR-related genes. PMID: 30097784
    2. In conclusion, we report a novel mutation in ZNF408 causing autosomal recessive retinitis pigmentosa with vitreal alterations in three members of a Tunisian family, which further accentuates the role of this new gene in the susceptibility to retinitis pigmentosa. PMID: 28095122
    3. Several novel mutations (missense, non-stop and insertion) were detected in the coding regions of FZD4, TSPAN12 and ZNF408 genes among the unrelated vitreoretinopathy probands. PMID: 27316669
    4. ZNF408, previously associated with Familial Exudative Vitreoretinopathy (FEVR), is a new gene causing autosomal recessive rtinitis pigmentosa. PMID: 25882705
    5. Data indicate ZNF408 missense variant (p.Ser126Asn) in 132 familial exudative vitreoretinopathy (FEVR) individuals in a Japanese family. PMID: 23716654

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  • 相關(guān)疾病：
    Vitreoretinopathy, exudative 6 (EVR6); Retinitis pigmentosa 72 (RP72)
  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Highest expression is observed in adult retina; abundantly expressed in the fetal eye. In the retina, it is detected in the outer nuclear layer, especially cone and rod photoreceptor cells, ganglion cell layer and both outer and inner plexiform layers (at
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20041

    OMIM: 616454

    KEGG: hsa:79797

    STRING: 9606.ENSP00000309606

    UniGene: Hs.656931



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