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ZNF274 Antibody, FITC conjugated

  • 中文名稱：
    ZNF274兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA850299LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ZNF274 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    ZNF274 antibody; ZKSCAN19 antibody; SP2114Neurotrophin receptor-interacting factor homolog antibody; Zinc finger protein 274 antibody; Zinc finger protein HFB101 antibody; Zinc finger protein with KRAB and SCAN domains 19 antibody; Zinc finger protein zfp2 antibody; Zf2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions.
  • 基因功能參考文獻(xiàn)：
    1. A proximal promoter construct for the MAS gene was repressed by the SOX [SRY (sex-determining region on the Y chromosome) box] proteins SRY, SOX2, SOX3 and SOX14, of which SRY is known to interact with the KRAB domain. PMID: 24128372
  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus, nucleolus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13068

    OMIM: 605467

    KEGG: hsa:10782

    STRING: 9606.ENSP00000321209

    UniGene: Hs.83761



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