ZNF175 Antibody

中文名稱：

ZNF175兔多克隆抗體
貨號：

CSB-PA026556LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026556LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ZNF175 Polyclonal antibody
Uniprot No.：

Q9Y473
基因名：

ZNF175
別名：

OTK18 antibody; Zinc finger protein 175 antibody; Zinc finger protein OTK18 antibody; ZN175_HUMAN antibody; ZNF175 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Zinc finger protein 175 protein (1-711AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，ZNF175 Antibody (CSB-PA026556LA01HU)，的標記方式是Non-conjugated。對于ZNF175 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA026556LB01HU	ZNF175 Antibody, HRP conjugated	ELISA
FITC	CSB-PA026556LC01HU	ZNF175 Antibody, FITC conjugated
Biotin	CSB-PA026556LD01HU	ZNF175 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
基因功能參考文獻：
1. Transcriptional suppressor OTK18 plays a role in macrophage control of viral replication during advanced HIV-1 infection. PMID: 14688346
2. OTK18/zinc finger protein 175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. PMID: 15081264
3. Plasma OTK18 levels are positively correlated to CD8 T-cell counts, independent of HIV-1 status. PMID: 18773297
4. These results suggest a role for OTK18 in innate immunity. PMID: 18776638
5. These data suggest that calpain and proteasome are involved in OTK18 endoproteolysis and degradation PMID: 19034669
6. HIV-1 induces OTK18 expression through a YIN-YANG-1 mediated manner in human macrophages PMID: 19034670
7. OTK18 may play a role in neurotrophin production and consequently support neuronal survival. PMID: 19247725
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亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 12964

OMIM: 601139

KEGG: hsa:7728

STRING: 9606.ENSP00000262259

UniGene: Hs.119014

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