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  4. ZNF175 Antibody

ZNF175 Antibody

  • 中文名稱：
    ZNF175兔多克隆抗體
  • 貨號：
    CSB-PA026556LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026556LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ZNF175 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZNF175
  • 別名：
    OTK18 antibody; Zinc finger protein 175 antibody; Zinc finger protein OTK18 antibody; ZN175_HUMAN antibody; ZNF175 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein 175 protein (1-711AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ZNF175 Antibody (CSB-PA026556LA01HU)，的標記方式是Non-conjugated。對于ZNF175 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA026556LB01HU ZNF175 Antibody, HRP conjugated ELISA
    FITC CSB-PA026556LC01HU ZNF175 Antibody, FITC conjugated
    Biotin CSB-PA026556LD01HU ZNF175 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
  • 基因功能參考文獻：
    1. Transcriptional suppressor OTK18 plays a role in macrophage control of viral replication during advanced HIV-1 infection. PMID: 14688346
    2. OTK18/zinc finger protein 175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. PMID: 15081264
    3. Plasma OTK18 levels are positively correlated to CD8 T-cell counts, independent of HIV-1 status. PMID: 18773297
    4. These results suggest a role for OTK18 in innate immunity. PMID: 18776638
    5. These data suggest that calpain and proteasome are involved in OTK18 endoproteolysis and degradation PMID: 19034669
    6. HIV-1 induces OTK18 expression through a YIN-YANG-1 mediated manner in human macrophages PMID: 19034670
    7. OTK18 may play a role in neurotrophin production and consequently support neuronal survival. PMID: 19247725

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  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 12964

    OMIM: 601139

    KEGG: hsa:7728

    STRING: 9606.ENSP00000262259

    UniGene: Hs.119014



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