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ZIP1 Antibody

Rare Species
  • 中文名稱:
    ZIP1兔多克隆抗體
  • 貨號(hào):
    CSB-PA339148XA11SVG
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: ZIP1 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 40 kDa
      Observed band size: 40 kDa
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    ZIP1
  • 別名:
    Synaptonemal complex protein ZIP1, ZIP1
  • 反應(yīng)種屬:
    S. cerevisiae
  • 免疫原:
    Recombinant S. cerevisiae ZIP1 protein (603-875aa)
  • 免疫原種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Affinity-chromatography
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, WB
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.
  • 基因功能參考文獻(xiàn):
    1. We discuss a model in which central element proteins are core building blocks that stabilize the architecture of SC near Zip1's N termini PMID: 24098146
    2. Data demonstrate that chromosomes are preloaded with Zip1p in a manner that may promote synapsis. PMID: 20375150
    3. Different functions of Zip1 display differential sensitivities to changes in expression levels. PMID: 19714362
    4. zip1 promotes the segregation of nonexchange chromosomes that are not tethered byp zip1 at centromeres. PMID: 20080752
    5. description of a process in meiotic cells in which chromosomes become joined together in pairs at their centromeres independent of chromosomal homology; these centromeric interactions depend on the synaptonemal complex component Zip1 PMID: 15879219
    6. The zip1-4LA defect in recombination is an indirect consequence of cell cycle arrest. PMID: 17435220
    7. Zip1 and Hop1 Occur with Differential Hyperabundance Along Pachytene Chromosomes; Differential Hop1/Zip1 Hyperabundance Depends on Pch2 PMID: 18305165

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  • 亞細(xì)胞定位:
    Nucleus. Chromosome. Note=Synapsed meiotic chromosomes.
  • 數(shù)據(jù)庫鏈接:

    KEGG: sce:YDR285W

    STRING: 4932.YDR285W



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