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  4. ZIC5 Antibody

ZIC5 Antibody

  • 中文名稱：
    ZIC5兔多克隆抗體
  • 貨號：
    CSB-PA850433LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA850433LA01HU diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ZIC5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZIC5
  • 別名：
    zic5 antibody; ZIC5_HUMAN antibody; Zinc finger protein of the cerebellum 5 antibody; Zinc finger protein ZIC 5 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein ZIC 5 protein (217-276AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ZIC5 Antibody (CSB-PA850433LA01HU)，的標記方式是Non-conjugated。對于ZIC5 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA850433LB01HU ZIC5 Antibody, HRP conjugated ELISA
    FITC CSB-PA850433LC01HU ZIC5 Antibody, FITC conjugated
    Biotin CSB-PA850433LD01HU ZIC5 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.
  • 基因功能參考文獻：
    1. hsa_circ_0007534 serves as an oncogene in glioma via promoting ZIC5 expression by repressing miR-761 availability. PMID: 29605301
    2. ZIC5 positively regulated the proliferation, migration, and survival of prostate colorectal cancer cells PMID: 29024195
    3. ZIC5 is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene by influencing CCNB1 and CDK1 complex expression PMID: 27663664
    4. ZIC1, ZIC2, and ZIC5 may have roles in meningiomas PMID: 20199689
    5. the smallest 13q deletion associated to DWM allows further narrowing of the previously established critical region for this brain malformation to 13q32.2-32.3. Among the few genes of the deleted region, ZIC2 and ZIC5 seem the most plausible candidates. PMID: 20683983

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    GLI C2H2-type zinc-finger protein family
  • 數據庫鏈接：

    HGNC: 20322

    OMIM: 617896

    KEGG: hsa:85416

    STRING: 9606.ENSP00000267294

    UniGene: Hs.508570



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