在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ZHX2 Antibody

  • 中文名稱:
    ZHX2兔多克隆抗體
  • 貨號:
    CSB-PA008272
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ZHX2
  • 別名:
    AFP regulator 1 antibody; AFR1 antibody; Alpha fetoprotein regulator 1 antibody; Alpha-fetoprotein regulator 1 antibody; KIAA0854 antibody; RAF antibody; Regulator of AFP antibody; Transcription factor ZHX2 antibody; ZHX2 antibody; ZHX2_HUMAN antibody; Zinc finger and homeodomain protein 2 antibody; Zinc fingers and homeoboxes 2 antibody; Zinc fingers and homeoboxes protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human ZHX2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex.
  • 基因功能參考文獻:
    1. These studies reveal ZHX2 as a potential therapeutic target for clear cell renal cell carcinoma. PMID: 30026228
    2. ZHX2 expression in renal cell carcinoma PMID: 28152006
    3. Zhx2 is a novel regulator of Mup expression; Zhx2 activates as well as represses expression of target genes PMID: 28258223
    4. These results indicated that ZHX2 plays a critical role in the proliferation and osteo/odontogenic differentiation of SCAPs. PMID: 26679602
    5. Data show that Zinc-fingers and homeoboxes 2 (ZHX2) represses nuclear transcription factor Y alpha (NF-Y)-mediated activation of multidrug resistance 1 (MDR1) transcription. PMID: 25473899
    6. Data indicate that zinc-fingers and homeoboxes 2 (ZHX2) suppresses glypican 3 (GPC3) transcription by binding with its core promoter. PMID: 25195714
    7. Two novel markers, rs7840785 (PINX1) and rs7844465 (ZHX2), are significantly associated with carotid intima-media thickness. PMID: 25746325
    8. simultaneous application of ZFN and rescue DNA induced gene repair of the disease-causing mutation on the genomic level, resulting in recovery of protein expression. PMID: 22661463
    9. Expression of a constitutively active Raf transgene enhances lymphoproliferation, indicating a role for the Ras-MAPK pathway in linker for activation of T cells (LAT)-mediated autoimmune hyperproliferation. PMID: 22984075
    10. There was no significant difference in high and low percentage of HbF in GG, GA, and AA bearing individuals showing that ZHX2 gene variant has no role in ameliorating the severity of beta-thalassemia major in the South Indian population from Andhra Pradesh. PMID: 21443521
    11. results demonstrate multiple mechanisms decreasing expression of tumor suppressor gene ZHX2 in Hodgkin lymphoma cell lines PMID: 22078940
    12. Expression profiling of L-1236 cells following siRNA-mediated knockdown of ZHX2 showed inhibition of genes regulating differentiation and apoptosis, suggesting tumor suppressor activity of ZHX2. PMID: 21987443
    13. identification as a transcriptional repressor PMID: 12741956
    14. ZHX2, a transcriptional repressor, may participate in globin gene regulation. PMID: 16952470
    15. High ZHX2 is associated with metastasis in hepatocellular carcinoma. PMID: 17447851
    16. These data support the idea that ZHX2 contributes to AFP repression in the liver after birth and may also be involved in AFP reactivation in liver cancer. PMID: 18194454

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    ZHX family
  • 組織特異性:
    Ubiquitously expressed. Expressed in podocytes.
  • 數據庫鏈接:

    HGNC: 18513

    OMIM: 609185

    KEGG: hsa:22882

    STRING: 9606.ENSP00000314709

    UniGene: Hs.377090



主站蜘蛛池模板: 女人被弄到高潮的免费视频 | 四虎国产精品亚洲一区久久特色| 怡春院久久国语视频免费| 亚洲成亚洲成网| 亚洲一区二区三区含羞草| 天堂а√中文在线官网| 国产jjzzjjzz视频全部免费| 成人自慰女黄网站免费大全| 国产99视频精品免视看7| 国产看黄网站又黄又爽又色| 伊人久久精品在热线热| 麻豆人妻无码性色av专区| 国产无吗一区二区三区在线欢| 国产精品99久久久精品无码| 亚洲人成网站在线播放小说 | 无码av最新高清无码专区| 成人动漫综合网| 欧美熟妇性开放| 久久精品人人槡人妻人人玩av | 强行糟蹋人妻hd中文字| 男女又色又爽又爽视频| 宅宅午夜无码一区二区三区| 无码超乳爆乳中文字幕| 日本肉体xxxx裸交| 国产aⅴ爽av久久久久久| 色夜码无码av网站| 亚洲日韩成人av无码网站| 久久精品农村毛片| 67194熟妇人妻欧美日韩| 丰满少妇人妻无码专区| 香蕉久久人人97超碰caoproen| 久久人妻天天av| 激情偷乱人成视频在线观看| 人人澡人人澡人人看添av| 乌克兰少妇xxxx做受| 免费无码成人片| 在线无码免费的毛片视频| 特黄做受又粗又大又硬老头| 丰满少妇弄高潮了www| 亚洲综合日韩久久成人av | 色欲综合一区二区三区|