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  4. ZC4H2 Antibody, Biotin conjugated

ZC4H2 Antibody, Biotin conjugated

  • 中文名稱：
    ZC4H2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA873628LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ZC4H2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZC4H2
  • 別名：
    HCA127 antibody; Hepatocellular carcinoma-associated antigen 127 antibody; KIAA1166 antibody; OTTHUMP00000023432 antibody; Zc4h2 antibody; ZC4H2_HUMAN antibody; Zinc finger C4H2 domain containing antibody; Zinc finger C4H2 domain-containing protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger C4H2 domain-containing protein (1-224AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in interneurons differentiation. Involved in neuronal development and in neuromuscular junction formation.
  • 基因功能參考文獻：
    1. The present patient confirms that female carriers can also be severely affected. Systematic clinical investigations of both males and females are needed to define the variety in nature and severity of phenotypes related to ZC4H2 variants. PMID: 28345801
    2. ZC4H2, an XLID gene, is required for the generation of a specific subset of CNS interneurons PMID: 26056227
    3. ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity. PMID: 23623388
  • 相關疾病：
    Wieacker-Wolf syndrome (WRWF)
  • 亞細胞定位：
    Cytoplasm. Nucleus. Cell junction, synapse, postsynaptic cell membrane. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites.
  • 組織特異性：
    Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle. Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord.
  • 數據庫鏈接：

    HGNC: 24931

    OMIM: 300897

    KEGG: hsa:55906

    STRING: 9606.ENSP00000363972

    UniGene: Hs.28249



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