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  4. ZC3H7B Antibody

ZC3H7B Antibody

  • 中文名稱：
    ZC3H7B兔多克隆抗體
  • 貨號：
    CSB-PA000061
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 293 cells using RoXaN Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ZC3H7B
  • 別名：
    ZC3H7B antibody; KIAA1031 antibody; Zinc finger CCCH domain-containing protein 7B antibody; Rotavirus 'X'-associated non-structural protein antibody; RoXaN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human RoXaN.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 'ATA(A/T)' motif in the apical loop.
  • 基因功能參考文獻：
    1. we find that ESS with ZC3H7B-BCOR fusion constitutes a novel type of high-grade endometrial stromal sarcoma and shares significant morphologic overlap with myxoid leiomyosarcoma. PMID: 27631520
    2. ZC3H7B-BCOR and MEAF6-PHF1 fusions occurred predominantly in S100 protein-negative and malignant ossifying fibromyxoid tumors. PMID: 24285434
    3. The present study further expands the genetic spectrum of small blue round cell tumors, with 2 novel fusions, BCOR-MAML3 and ZC3H7B-BCOR, identified PMID: 26752546
    4. Reverse transciptase-PCR with the ZC3H7B forward and BCOR reverse primer combinations confirmed the presence of a ZC3H7-BCOR chimeric transcript in both ESS carrying a der(22)t(X;22) but not in a control ESS with t(1;6) and the MEAF6-PHF1 fusion. PMID: 23580382
    5. RoXaN is capable of interacting with NSP3 and eIF4G I in vivo and during rotavirus infection. Domains of interaction were mapped. PMID: 15047801
    6. nuclear localization of PABP-C1 not only is dependent on the capacity of rotavirus NSP3 to interact with eIF4G but also requires the interaction of NSP3 with a specific region in RoXaN PMID: 18799579

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  • 亞細胞定位：
    Nucleus. Note=Nuclear localization seems to be depleted upon rotavirus A infection.
  • 數據庫鏈接：

    HGNC: 30869

    KEGG: hsa:23264

    STRING: 9606.ENSP00000263243

    UniGene: Hs.592188



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