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YPEL3 Antibody

  • 中文名稱:
    YPEL3兔多克隆抗體
  • 貨號:
    CSB-PA026272LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026272LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) YPEL3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    YPEL3
  • 別名:
    Protein yippee-like 3 antibody; Small ubiquitinated apoptotic protein antibody; Yippee like 3 antibody; Yippee-like 3 (Drosophila) antibody; Ypel3 antibody; YPEL3_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein yippee-like 3 protein (1-119AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,YPEL3 Antibody (CSB-PA026272LA01HU),的標記方式是Non-conjugated。對于YPEL3 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA026272LB01HU YPEL3 Antibody, HRP conjugated ELISA
    FITC CSB-PA026272LC01HU YPEL3 Antibody, FITC conjugated
    Biotin CSB-PA026272LD01HU YPEL3 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in proliferation and apoptosis in myeloid precursor cells.
  • 基因功能參考文獻:
    1. Expression of the YPEL3 gene was upregulated in human colonic adenocarcinoma tissue. PMID: 29988027
    2. Data show that YPEL3 is downregulated in nasopharyngeal carcinoma (NPC) cell lines and tissue samples and it suppresses NPC EMT and metastasis by suppressing the Wnt/beta-catenin signaling pathway. PMID: 27400785
    3. YPEL3 expression, which is induced by the removal of estrogen or treatment with tamoxifen triggers cellular senescence in MCF-7 cells while loss of YPEL3 increases the growth rate of MCF-7 cells. PMID: 21671470
    4. YPEL3 is downregulated in colon tumors. PMID: 21267786
    5. In this review we show that transcriptionally active forms of p73 and p63, family members of p53, can transactivate the human YPEL3 gene[review] PMID: 21196260
    6. Findings point to YPEL3 being a novel tumor suppressor, which upon induction triggers a permanent growth arrest in human tumor and normal cells. PMID: 20388804

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  • 亞細胞定位:
    Nucleus, nucleolus.
  • 蛋白家族:
    Yippee family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 18327

    OMIM: 609724

    KEGG: hsa:83719

    STRING: 9606.ENSP00000381821

    UniGene: Hs.513491



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