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  4. YKT6 Antibody, HRP conjugated

YKT6 Antibody, HRP conjugated

  • 中文名稱：
    YKT6兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA026265LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) YKT6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    YKT6
  • 別名：
    R SNARE antibody; SNARE protein Ykt6 antibody; Synaptobrevin homolog YKT6 antibody; YKT 6 antibody; YKT6 antibody; YKT6 S. cerevisiae homolog of antibody; YKT6 v SNARE homolog antibody; YKT6 v SNARE protein antibody; YKT6_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Synaptobrevin homolog YKT6 protein (10-195AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.
  • 基因功能參考文獻：
    1. YKT6 is a key molecule in the regulation of exosome release in lung cancer cells and is in turn precisely regulated by miR-134 and miR-135b. Moreover, YKT6 levels impact prognosis of resected Non small cell lung cancer patients. PMID: 27285987
    2. abnormalities in the SNARE complex could represent a molecular substrate for abnormalities of neural connectivity in severe mental disorders PMID: 11884350
    3. Data suggest that GS15 exists in a distinct SNARE complex that contains syntaxin5, GS28, and Ykt6, and may be involved in both ER-to-Golgi and intra-Golgi transport. PMID: 12388752
    4. N-ethylmaleimide-sensitive factor-dependent SNARE-priming complex disassembly is required for efficient exocytosis from mast cells. PMID: 14607937
    5. mRNA expression of CCT5, RGS3, and YKT6 was significantly up-regulated in p53-mutated tumors and associated with a low response rate to docetaxel. PMID: 16821082

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  • 亞細胞定位：
    Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Probably cycles through vesicles between Golgi and endosomes.
  • 蛋白家族：
    Synaptobrevin family
  • 數據庫鏈接：

    HGNC: 16959

    OMIM: 606209

    KEGG: hsa:10652

    STRING: 9606.ENSP00000223369

    UniGene: Hs.520794



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