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Your Good Partner in Biology Research

YEATS2 Antibody

  • 中文名稱:
    YEATS2兔多克隆抗體
  • 貨號:
    CSB-PA004540
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of 293 cells using YEATS2 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    YEATS2
  • 別名:
    FLJ10201 antibody; FLJ12841 antibody; FLJ13308 antibody; FLJ33401 antibody; FLJ34335 antibody; KIAA1197 antibody; YEATS domain containing 2 antibody; YEATS domain-containing protein 2 antibody; Yeats2 antibody; YETS2_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human YEATS2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.
  • 基因功能參考文獻:
    1. YEATS2 is a selective histone crotonylation reader. PMID: 27103431
    2. YEATS2 gene is highly amplified in human non-small cell lung cancer (NSCLC) and is required for cancer cell growth and survival PMID: 29057918
  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 25489

    OMIM: 613373

    KEGG: hsa:55689

    STRING: 9606.ENSP00000306983

    UniGene: Hs.632575



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