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Y10A Antibody

Rare Species
  • 中文名稱:
    Y10A Antibody
  • 貨號:
    CSB-PA327123XA01EDZ
  • 規格:
    ¥880
  • 圖片:
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:Y10A Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 38 kDa
      Observed band size: 38 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Enterobacteria phage T4 (Bacteriophage T4) Y10A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    Y10A
  • 別名:
    RNA ligase 2 (Rnl2) (EC 6.5.1.3) Y10A 24.1
  • 宿主:
    Rabbit
  • 反應種屬:
    Enterobacteria phage T4 (Bacteriophage T4)
  • 免疫原:
    Recombinant Enterobacteria phage T4 (Bacteriophage T4) Y10A protein (1-249aa)
  • 免疫原種屬:
    Enterobacteria phage T4 (Bacteriophage T4)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Repairs 3'-OH/5'-PO4 nicks in duplex RNA or RNA:DNA hybrid in which the broken 3'-OH strand is RNA. The nick ligation reaction entails three nucleotidyl transfer steps. In the first step, the RNA ligase reacts with ATP in the absence of nucleic acid to form a covalent ligase-AMP intermediate and release pyrophosphate. In step 2, the ligase-AMP binds to the nicked duplex nucleic acid and transfers the adenylate to the 5'-PO4 terminus to form an adenylylated nicked intermediate. In step 3, the RNA ligase directs the attack of the nick 3'-OH on the 5'-phosphoanhydride linkage, resulting in a repaired 3' - 5' phosphodiester and release of AMP.
  • 基因功能參考文獻:
    1. To unravel the biochemical and functional relationship between Rnl1, Rnl2, and Dnl, a systematic analysis of their substrate specificity was performed using recombinant proteins PMID: 16671895
    2. Results report crystal structures for T4 RNA ligase 2 (Rnl2) at discrete steps along the RNA repair pathway. PMID: 17018278
  • 蛋白家族:
    RNA ligase 2 family
  • 數據庫鏈接:

    KEGG: vg:1258563



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