在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

WRNIP1 Antibody

  • 中文名稱:
    WRNIP1兔多克隆抗體
  • 貨號(hào):
    CSB-PA026150GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    WRNIP1
  • 別名:
    ATPase WRNIP 1 antibody; ATPase WRNIP1 antibody; bA420G6.2 antibody; FLJ22526 antibody; Putative helicase RUVBL antibody; RP11 420G6.2 antibody; Werner helicasae interacting protein 1 antibody; Werner helicasae interacting protein antibody; Werner helicase interacting protein isoform 2 antibody; Werner helicase-interacting protein 1 antibody; WHIP antibody; WRIP1_HUMAN antibody; WRNIP 1 antibody; WRNIP antibody; Wrnip1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human WRNIP1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG-I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS.
  • 基因功能參考文獻(xiàn):
    1. findings define the WHIP-TRIM14-PPP6C mitochondrial signalosome required for RIG-I-mediated innate antiviral immunity. PMID: 29053956
    2. The authors show that WRNIP1 is directly involved in preventing uncontrolled MRE11-mediated degradation of stalled replication forks by promoting RAD51 stabilization on ssDNA. PMID: 27242363
    3. We propose that UBZ domains can be divided into at least two different types in terms of the ubiquitin-binding surfaces: the pol type and the WRNIP1 type PMID: 27062441
    4. results suggest that WRNIP1 functions upstream of Poleta in the response to UV irradiation PMID: 25139235
    5. Mutated WRNIP1 with a deleted ATPase domain or with mutations in lysine residues accumulated in laser light irradiated sites, suggesting that the ATPase domain of WRNIP1 and ubiquitination of WRNIP1 are dispensable for the accumulation. PMID: 22209848
    6. WHIP was identified as a partner/component of the nuclear envelope/nuclear pore complex (NPC) and set forth to investigate a role for the protein positioned at the NPC. PMID: 20676042
    7. These results indicate that WRNIP1 functions as a modulator for initiation or restart events during pol delta-mediated DNA synthesis and that its ATPase activity is utilized to sense DNA ends and to regulate the extent of stimulation. PMID: 15670210
    8. Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain PMID: 17550899
    9. analysis of the composite and regulated topography of Wrnip1 in the human nucleus highlights its potential role in replication and other nuclear transactions PMID: 18842586

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    AAA ATPase family, RarA/MGS1/WRNIP1 subfamily
  • 組織特異性:
    Ubiquitously expressed.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 20876

    OMIM: 608196

    KEGG: hsa:56897

    STRING: 9606.ENSP00000370150

    UniGene: Hs.236828



主站蜘蛛池模板: 欧美亚洲国产一区二区三区 | 色妞精品av一区二区三区| 三级成年网站在线观看级爱网| 国产av无码专区亚洲aⅴ| 色婷婷综合缴情综免费观看| 中文在线а天堂中文在线新版| 国产精品国产自线拍免费不卡| 色欲av蜜桃一区二区三| 国产成人片无码视频在线观看| 日本乱妇乱子视频网站-百度| 免费国产h视频在线观看| 国产精品va在线观看h| 亚洲国产精品久久久久婷婷老年| 四虎永久在线精品无码视频| 任你躁久久精品6| 国产成人精选在线观看不卡| 国产精品美女一区二区三区| 日本黄页网站免费观看| 久久久久久久波多野结衣高潮| 国产重口老太和小伙| 免费观看羞羞视频网站| 国产精品成人亚洲777| 亚洲国产成人久久一区| 性欧美vr高清极品| 日韩乱码人妻无码系列中文字幕| 国产av久久久久精东av| 已婚少妇美妙人妻系列| 国产情侣真实露脸在线| 99热亚洲色精品国产88| 国产午夜福利伦理300| 熟女人妻大叫粗大受不了| 在线高清亚洲精品二区| h漫全彩纯肉无码网站| 一边摸一边抽搐一进一出视频| 亚洲精品国产熟女久久久| 97久久超碰精品视觉盛宴| 色妞ww精品视频7777| 伊人色综合久久天天| 亚洲国产精品av在线播放| 国内精品久久久久影院日本 | 亚洲欧洲精品无码av|