在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

WNT11 Antibody

  • 中文名稱(chēng):
    WNT11兔多克隆抗體
  • 貨號(hào):
    CSB-PA437651
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA437651(WNT11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA437651(WNT11 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    HWNT11 antibody; Protein Wnt-11 antibody; Wingless-related MMTV integration site 11 antibody; Wingless-type MMTV integration site family, member 1 antibody; Wingless-type MMTV integration site family, member 11 antibody; Wingless-type MMTV integration site family, member 11B antibody; wnt-11 antibody; wnt11 antibody; WNT11_HUMAN antibody; wnt11b antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human WNT11
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
  • 基因功能參考文獻(xiàn):
    1. FZD8 co-localizes and co-immunoprecipitates with Wnt-11 and potentiates Wnt-11 activation of ATF2-dependent transcription PMID: 29717114
    2. we found that the hypoxic environment of the perivenular zone promotes Wnt11 expression in hepatocytes, which then regulates unique gene expression via activation of the non-canonical Wnt pathway PMID: 29244788
    3. TGF-beta1-induced sm-alpha-actin expression is mediated by WNT-11 via RhoA activation and subsequent actin cytoskeletal remodeling. PMID: 27422998
    4. The positive rates of Wnt11 protein in normal esophageal epithelium tissue was 29.8% and in esophageal carcinomas tissue was 31.9%; there was no significant difference between the two groups PMID: 27628667
    5. Data suggest that Wnt-11 may serve as a target for cervical cancer therapy. PMID: 27034261
    6. The Wnt11 gene plays an important role in human mesenchymal stromal cells for enhancing the osteogenesis in an infectious environment. PMID: 26818191
    7. Demonstrate immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. PMID: 27386628
    8. Report high expression of Wnt11 in esophageal squamous cell carcinoma, which was significantly associated with AJCC stage. PMID: 26261605
    9. Notch1-induced WISP-1 expression appeared to be Wnt11-dependent, but Wnt1-independent PMID: 22715413
    10. High expression of Wnt-11 is associated with metastasis in cervical cancer. PMID: 24737009
    11. Data established a seven-gene (AR, ESR2, GATA3, GBX2, KRT16, MMP28 and WNT11) prognostic signature to define a subset of triple-negative breast cancer (TNBC). PMID: 23549873
    12. Estrogen/progesterone treatment of mature myometrial cells induced expression of WNT11 and WNT16, which remained constitutively elevated in leiomyoma tissues. PMID: 24082114
    13. Wnt11 mRNA expression was significantly higher in the stage I, II, III, or IV colorectal tumor tissues than in non-tumor colon. PMID: 22161723
    14. Wnt11 is involved in the protection of the host intestinal cells by blocking the invasion of pathogenic bacteria, suppressing inflammation, and inhibiting apoptosis. PMID: 21903761
    15. WNT11 emerged as a direct target of ERG. PMID: 21242973
    16. These observations highlight the distinct roles of WNT11 and WNT4 during the early stages of retinoic acid-induced neuronal differentiation. PMID: 21280163
    17. Data provide evidence for an autocrine regulatory loop involving transcriptional upregulation of WNT11 by ERRalpha and beta-cat that influences the migratory capacity of cancer cells. PMID: 20870744
    18. These observations suggest a novel role for Wnt11 as a tumor suppressor during hepatocarcinogenesis because loss of expression promotes the malignant phenotype via both canonical and noncanonical Wnt signaling pathways. PMID: 20103596
    19. These observations suggest that the increased level of Wnt-11 found in prostate cancer contributes to tumour progression by promoting neuroendocrine-like differentiation. PMID: 20219091
    20. WNT11 mRNA was up-regulated in four cases of colorectal adenocarcinoma, and a case of renal cell carcinoma. Up-regulation of WNT11 mRNA might play an important role in human carcinogenesis through activation of the WNT signaling pathway. PMID: 11712081
    21. Wnt11 stimulates proliferation, migration, cytoskeletal rearrangement, and contact-independent growth by a beta-catenin-independent mechanism PMID: 15084607
    22. Wnt11 promotes cardiac differentiation via the non-canonical PKC-dependent signaling pathway PMID: 15701629
    23. Wnt11 gene is expressed during early embryonic development and has a critical role in regulation of gastrulation movements. PMID: 15708567
    24. Wnt-11 promotes cell viability and is involved in coordination of key signaling pathways. PMID: 18572162
    25. Our study reveals an unappreciated role for noncanonical Wnt signaling in hESC specification that involves development of unique mesoderm precursors via morphogenic organization within human EBs. PMID: 19265664

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Wnt family
  • 組織特異性:
    Expressed in fetal lung, kidney, adult heart, liver, skeletal muscle, and pancreas.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 12776

    OMIM: 603699

    KEGG: hsa:7481

    STRING: 9606.ENSP00000325526

    UniGene: Hs.108219



主站蜘蛛池模板: 亚洲另类欧美小说图片区| 国产成人a人亚洲精v品无码| 7777奇米四色成人眼影| 国内精品人妻久久毛片app| 精品无码一区二区三区爱欲九九| 蜜臀av99无码精品国产专区| 7777精品伊久久久大香线蕉| 五月激情婷婷丁香综合基地| 亚洲精品久久久久中文字幕| 97精品一区二区视频在线观看| 狂野av人人澡人人添| 天堂√最新版中文在线天堂| 天天躁夜夜躁狠狠综合2020| 国产综合内射日韩久| 爱做久久久久久| 天天综合天天爱天天做| 国产精品女上位好爽在线| 尤物色综合欧美五月俺也去| 午夜dj在线观看高清在线视频完整版| 后入内射无码人妻一区| 国产suv精品一区二区883| 亚洲欧洲日产最新| 无线乱码一二三区免费看| 强行无套内谢大学生初次| 久久国产精品99国产精| 亚洲欧洲无卡二区视頻| 99久久免费国产精品四虎| 亚洲色无码专区在线观看| 亚洲日本在线电影| 草草影院发布页| 影音先锋在线亚洲网站| 国内精品乱码卡一卡2卡| 正在播放国产真实露脸高清| 国产免费无码一区二区三区| 无尺码精品产品视频| 丁香五月婷激情综合第九色| 欧美亚洲熟妇一区二区三区| 影视先锋av资源噜噜| 国产xxxxx在线观看| 亚洲精品国产品国语原创| 一区二区和激情视频|