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WDR59 Antibody

  • 中文名稱：
    WDR59兔多克隆抗體
  • 貨號：
    CSB-PA764810LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of U251 cells with CSB-PA764810LA01HU at 1:173, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Western Blot
      Positive WB detected in: 293T whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate
      All lanes: WDR59 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 110, 65, 63, 47 kDa
      Observed band size: 110 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) WDR59 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    WDR59 antibody; KIAA1923 antibody; FP977 antibody; GATOR complex protein WDR59 antibody; WD repeat-containing protein 59 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human GATOR complex protein WDR59 protein (619-862AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，WDR59 Antibody (CSB-PA764810LA01HU)，的標記方式是Non-conjugated。對于WDR59 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA764810LB01HU WDR59 Antibody, HRP conjugated ELISA
    FITC CSB-PA764810LC01HU WDR59 Antibody, FITC conjugated
    Biotin CSB-PA764810LD01HU WDR59 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
  • 亞細胞定位：
    Lysosome membrane.
  • 蛋白家族：
    WD repeat WDR59 family
  • 數據庫鏈接：

    HGNC: 25706

    OMIM: 617418

    KEGG: hsa:79726

    STRING: 9606.ENSP00000262144

    UniGene: Hs.280951



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