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WDPCP Antibody

  • 中文名稱：
    WDPCP兔多克隆抗體
  • 貨號：
    CSB-PA528516LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA528516LA01HU at dilution of 1:100
    • Immunofluorescence staining of MCF-7 cells with CSB-PA528516LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) WDPCP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    WDPCP
  • 別名：
    Bardet-Biedl syndrome 15 protein antibody; Chromosome 2 open reading frame 86 antibody; DKFZp686C12204 antibody; Fritz antibody; FRITZ_HUMAN antibody; hFrtz antibody; WD repeat containing protein C2orf86 antibody; WD repeat-containing and planar cell polarity effector protein antibody; WD repeat-containing and planar cell polarity effector protein fritz homolog antibody; WDPCP antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human WD repeat-containing and planar cell polarity effector protein fritz homolog protein (621-737AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，WDPCP Antibody (CSB-PA528516LA01HU)，的標記方式是Non-conjugated。對于WDPCP Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA528516LB01HU WDPCP Antibody, HRP conjugated ELISA
    FITC CSB-PA528516LC01HU WDPCP Antibody, FITC conjugated
    Biotin CSB-PA528516LD01HU WDPCP Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies.
  • 基因功能參考文獻：
    1. Inflammatory cytokines cause reduced WDPCP expression, which contributes to impaired ciliogenesis in human rhinosinusitis. PMID: 28001338
    2. study linked mutations in Fritz to Bardet-Biedl and Meckel-Gruber syndromes, a notable link given that other genes mutated in these syndromes also influence collective cell movement and ciliogenesis PMID: 20671153
  • 相關疾病：
    Bardet-Biedl syndrome 15 (BBS15); Congenital heart defects, hamartomas of tongue, and polysyndactyly (CHDTHP)
  • 亞細胞定位：
    Cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    WD repeat fritz family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 28027

    OMIM: 217085

    KEGG: hsa:51057

    STRING: 9606.ENSP00000272321

    UniGene: Hs.414952



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