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  4. WDFY4 Antibody

WDFY4 Antibody

  • 中文名稱：
    WDFY4兔多克隆抗體
  • 貨號：
    CSB-PA025993GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    WDFY4
  • 別名：
    WDFY4 antibody; C10orf64 antibody; KIAA1607WD repeat- and FYVE domain-containing protein 4 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human WDFY4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
  • 基因功能參考文獻：
    1. A significantly increased risk for RA associated with the WDFY4 rs7097397 AG genotype. PMID: 24549174
    2. rs877819 SNP in WDFY4 may be associated with systemic lupus erythematosus by reduced binding of YY1 and downregulating WDFY4 expression. PMID: 22972472
    3. Genetic variants in ETS1 and WDFY4 were found to be associated with systemic lupus erythematosus, in the Asian population studied. PMID: 20169177
  • 亞細胞定位：
    Early endosome. Endoplasmic reticulum.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29323

    OMIM: 613316

    KEGG: hsa:57705

    STRING: 9606.ENSP00000320563

    UniGene: Hs.287379



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