在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. WBP2 Antibody, FITC conjugated

WBP2 Antibody, FITC conjugated

  • 中文名稱：
    WBP2兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA842628LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) WBP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    WBP2
  • 別名：
    MGC18269 antibody; WBP 2 antibody; WBP-2 antibody; Wbp2 antibody; WBP2_HUMAN antibody; WW domain binding protein 2 antibody; WW domain-binding protein 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human WW domain-binding protein 2 protein (1-261AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation. In presence of estrogen, binds to ESR1-responsive promoters. Required for YAP1 coactivation function on PGR activity. Synergizes with WBP2 in enhancing PGR activity. Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR.
  • 基因功能參考文獻：
    1. Data indicate WW-binding protein 2 (WBP2) as an important co-factor of YY1 associated protein 1 (YAP) that enhances YAP/TEAD-mediated gene transcription. PMID: 28332498
    2. WBP2/ITCH signaling functions to link the intricate Wnt and Hippo signaling networks in breast cancer. PMID: 27578003
    3. the miR-206/WBP2 axis can modulate tamoxifen sensitivity via regulating G1/S progression in estrogen receptor + breast cancer PMID: 28391353
    4. The authors reported that the loss of Wbp2 expression leads to progressive high-frequency hearing loss in mouse, as well as in two deaf children, each carrying two different variants in the WBP2 gene. PMID: 26881968
    5. data indicate that WBP-2 enhances ER transactivation function at certain genes by facilitating the recruitment and/or the stabilization of a histone modifier enzyme that favors a relaxed chromatin structure, permissive of transcription PMID: 23233354
    6. The WW1 and WW2 domains of YAP2 recognize various PPXY motifs within WBP2 and WBP1 in a highly promiscuous and subtle manner. PMID: 21981024
    7. Data show that direct interaction of Wbp2 with TAZ depends on the WW domain of TAZ. PMID: 20972459
    8. WW domain binding protein-2, an E6-associated protein interacting protein, acts together with YAP as coactivators of estrogen and progesterone receptors. PMID: 16772533

    顯示更多

    收起更多

  • 相關疾病：
    Deafness, autosomal recessive, 107 (DFNB107)
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 組織特異性：
    Ubiquitous.
  • 數據庫鏈接：

    HGNC: 12738

    OMIM: 606962

    KEGG: hsa:23558

    STRING: 9606.ENSP00000254806

    UniGene: Hs.514489



主站蜘蛛池模板： 精品国产av无码一区二区三区| 另类 专区 欧美 制服| 欧美高清性色生活片免费观看| 国产xxxx做受视频| 国产av久久人人澡人人爱| 亚拍精品一区二区三区探花| 777米奇影院狠狠色| 久青草国产在视频在线观看| 国产成人久久av免费| 男女下面进入的视频免费午夜| 真人性囗交69视频| 久久精品夜色噜噜亚洲a∨| 18禁黄网站禁片免费观看国产| 国产亚洲精品国产福利你懂的| 色综合视频一区二区三区44| 日本饥渴人妻欲求不满| 国产精品久久久久7777| 亚洲国产精品无码中文字满| 日本免费更新一二三区不卡| 男女做爰无遮挡性视频| 国产在线视频www色| 大乳丰满人妻中文字幕日本| 伊人久久精品在热线热| 国产亚洲日韩在线aaaa| 狠狠综合久久久久尤物| 国内精品久久久久影院一蜜桃| 午夜久久久久久禁播电影| 亚洲精品国产福利一区二区| 日本视频免费高清一本18| 亚洲欧洲日产国无高清码图片| 国产精品第12页| 中文字字幕在线中文乱码| 色六月婷婷亚洲婷婷六月| 97se色综合一区二区二区| 欧美老妇交乱视频在线观看 | 中文字幕一区在线观看视频| 国产无套中出学生姝| 亚洲欧美精品suv| 日韩人妻无码精品久久| 亚洲综合伊人久久大杳蕉| 90后极品粉嫩小泬20p|