在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. WAC Antibody, HRP conjugated

WAC Antibody, HRP conjugated

  • 中文名稱：
    WAC兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA861133HB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) WAC Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    WAC
  • 別名：
    1110067P07Rik antibody; BA48B24 antibody; BA48B24.1 antibody; BM 016 antibody; FLJ31290 antibody; KIAA1844 antibody; MGC10753 antibody; OTTHUMP00000019380 antibody; OTTHUMP00000019382 antibody; PRO1741 antibody; wac antibody; WAC_HUMAN antibody; WW domain containing adapter protein with coiled coil antibody; WW domain containing adaptor with coiled coil antibody; WW domain-containing adapter protein with coiled-coil antibody; Wwp4 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human WW domain-containing adapter protein with coiled-coil protein (10-102AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Interacts with the RNA polymerase II transcriptional machinery via its WW domain and with RNF20-RNF40 via its coiled coil region, thereby linking and regulating H2BK120ub1 and gene transcription. Regulates the cell-cycle checkpoint activation in response to DNA damage. Positive regulator of amino acid starvation-induced autophagy. Also acts as a negative regulator of basal autophagy. Positively regulates MTOR activity by promoting, in an energy-dependent manner, the assembly of the TTT complex composed of TELO2, TTI1 and TTI2 and the RUVBL complex composed of RUVBL1 and RUVBL2 into the TTT-RUVBL complex. This leads to the dimerization of the mTORC1 complex and its subsequent activation. May negatively regulate the ubiquitin proteasome pathway.
  • 基因功能參考文獻：
    1. Our observation allows us to redefine the smallest region of overlap among patients reported so far, with a size of 80 Kb and which contains only the WAC gene. These findings strengthen the hypothesis that haploinsufficency of WAC gene might be likely responsible for intellectual disability and behavior disorders. PMID: 27119754
    2. De novo WAC loss-of-function mutations were identified through exome sequencing of individuals with unexplained intellectual disability. PMID: 26757981
    3. WAC loss-of-function mutations cause a recognisable syndrome characterised by dysmorphic features, developmental delay and hypotonia and recapitulate 10p11.23 microdeletion syndrome PMID: 26264232
    4. The identification of SCOC and WAC as novel regulatory proteins with diverse functions in autophagy contributes towards a fuller understanding of autophagosome formation. PMID: 22354037
  • 相關(guān)疾病：
    DeSanto-Shinawi syndrome (DESSH)
  • 亞細胞定位：
    Nucleus speckle. Nucleus.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17327

    OMIM: 615049

    KEGG: hsa:51322

    STRING: 9606.ENSP00000346986

    UniGene: Hs.743224



主站蜘蛛池模板： 国产午夜成人无码免费| 人妻少妇av无码一区二区| 日产日韩亚洲欧美综合下载| 国产成人精品一区二区不卡| 麻花传媒mv国产免费观看视频| 日本丰满熟妇videossex8k| 7777精品久久久大香线蕉| 无遮挡男女激烈动态图| 激情综合丁香五月| 国模冰莲极品自慰人体| 在阳台上玩弄人妻的乳球 | 少妇无码av无码一区| 亚洲精品久久婷婷丁香51| 日本乱人伦在线观看| 狠狠色噜噜狠狠狠狠888奇禾| 国产超碰人人做人人爽av大片| 亚洲精品午夜国产va久久成人| 国产精品免费一区二区三区四区| 无码熟熟妇丰满人妻啪啪| 中文字幕 乱码 中文乱码视频| 揉着我的奶从后面进去视频| 成人艳情一二三区| 国产精品高潮呻吟av久久4虎 | 国产精品久久久久电影网| 国产av无码国产av毛片| 亚洲精品久久区二区三区蜜桃臀| 亚洲精品无码人妻无码| 亚洲精品揄拍自拍首页一| 国产午夜精品一区二区| 午夜福利片手机在线播放| 亚洲自偷自拍另类12p| 一区二区三区在线 | 欧洲| 日本牲交大片免费观看| 午夜内射中出视频| 五月婷婷久久草丁香| 天堂а√在线中文在线新版| 精品国产乱码久久久久久下载| 亚洲人成网站在小说| 国产精品毛片一区二区| 亚洲高清成人av电影网站| 日日摸处处碰夜夜爽|