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  4. VTI1B Antibody

VTI1B Antibody

  • 中文名稱：
    VTI1B兔多克隆抗體
  • 貨號：
    CSB-PA006555
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of RAT-HEART cells using v-SNARE Vti1p Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    VTI1B
  • 別名：
    HGNC:17793 antibody; V SNARE antibody; v-SNARE antibody; Vesicle associated soluble NSF attachment protein receptor antibody; Vesicle transport through interaction with t SNAREs 1B antibody; Vesicle transport through interaction with t SNAREs homolog 1B (yeast) antibody; Vesicle transport through interaction with t-SNAREs homolog 1B antibody; Vesicle transport v-SNARE protein Vti1-like 1 antibody; VTI1 antibody; VTI1 like antibody; Vti1 rp1 antibody; VTI1-LIKE antibody; Vti1-rp1 antibody; VTI1B antibody; VTI1B_HUMAN antibody; VTI1L antibody; VTI1L1 antibody; VTI2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human v-SNARE Vti1p.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
  • 基因功能參考文獻(xiàn)：
    1. Vti1b-dependent tethering of Lytic granule and CD3-endo determines accumulation, docking, and efficient lytic granule secretion at the immunological synapse. PMID: 21562157
    2. Results suggest that the combinational SNARE proteins VAMP8 and Vti1b mediate the fusion of antimicrobial and canonical autophagosomes with lysosomes, an essential event for autophagic degradation. PMID: 20089838
    3. A dual mechanism controlling the localization and function of exocytic v-SNAREs. PMID: 12853575
    4. Ca(2+) dissociates the Hrs-containing complex but not the VAMP-2-containing SNARE complex PMID: 14769786
    5. epsin 4 epsin-related protein is an adaptor for vti1b PMID: 15371541
    6. Results report that syntaxin 7, syntaxin 8, vti1b and VAMP8 physically and functionally interact with CFTR. PMID: 18570918

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  • 亞細(xì)胞定位：
    Early endosome membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane; Single-pass type IV membrane protein.
  • 蛋白家族：
    VTI1 family
  • 組織特異性：
    Expressed in all tissues examined.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17793

    OMIM: 603207

    KEGG: hsa:10490

    STRING: 9606.ENSP00000450731

    UniGene: Hs.741177



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