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VPS51 Antibody, Biotin conjugated

  • 中文名稱:
    VPS51兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA883424LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) VPS51 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    VPS51
  • 別名:
    ANG2 antibody; ANG3 antibody; Another new gene 2 protein antibody; C11orf3 antibody; chromosome 11 open reading frame 2 antibody; Fat free homolog antibody; ffr antibody; FFR_HUMAN antibody; FFR|FLJ13879 antibody; FLJ36472 antibody; Protein fat-free homolog antibody; Vacuolar protein sorting 51 homolog antibody; VPS51 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
  • 基因功能參考文獻:
    1. A dityrosine motif of Ang2 interacts with a highly conserved groove in Syntaxin 6. PMID: 23932592
    2. Ang2 is the missing component of the Golgi-associated retrograde protein complex in most eukaryotes. PMID: 20685960
  • 亞細胞定位:
    Golgi apparatus, trans-Golgi network. Recycling endosome.
  • 蛋白家族:
    VPS51 family
  • 數據庫鏈接:

    HGNC: 1172

    OMIM: 615738

    KEGG: hsa:738

    STRING: 9606.ENSP00000279281

    UniGene: Hs.277517



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