在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

VPS18 Antibody, FITC conjugated

  • 中文名稱:
    VPS18兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA882173LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) VPS18 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    hVPS18 antibody; PEP3 antibody; Vacuolar protein sorting 18 antibody; Vacuolar protein sorting protein 18 antibody; Vacuolar protein sorting-associated protein 18 homolog antibody; vps18 antibody; VPS18_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Vacuolar protein sorting-associated protein 18 homolog protein (298-515AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes. Involved in dendrite development of Pukinje cells.
  • 基因功能參考文獻:
    1. VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction PMID: 28931724
    2. Depletion of hVps18 or hMon2 reduced the efficient production of infectious HIV-1 virions in human cells. PMID: 21450827
    3. hVPS18 may play an important role in regulation of SNK activity through its ubiquitin ligase PMID: 16203730
    4. ubiquitin binding and ubiquitylation of GGA3-GAT domain are mutually inseparable through a ubiquitin ligase activity of hVPS18 PMID: 16996030
  • 亞細胞定位:
    Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Cytoplasmic, peripheral membrane protein associated with early endosomes and late endosomes/lysosomes.
  • 蛋白家族:
    VPS18 family
  • 組織特異性:
    Ubiquitous. Expression was highest in heart and low in lung.
  • 數據庫鏈接:

    HGNC: 15972

    OMIM: 608551

    KEGG: hsa:57617

    STRING: 9606.ENSP00000220509

    UniGene: Hs.23876



主站蜘蛛池模板: 日本黄漫动漫在线观看视频| 精品人妻系列无码人妻免费视频| 国产精品人成视频国模| 成人自慰女黄网站免费大全| 国产亚洲综合欧美一区二区| 中文字幕日韩一区二区三区不卡| 久久www成人_看片免费不卡| 国产乱人伦偷精品视频aaa| 新香蕉少妇视频网站| 欧美老熟妇牲交| 免费人成在线观看网站品善网| 台湾无码av一区二区三区| 国产日产精品一区二区三区四区的特点| 九九久久精品无码专区| 在线天堂www在线国语对白| 色舞月亚洲综合一区二区| 无码国内精品久久综合88| 天天躁夜夜躁狠狠眼泪| 国产亚洲综合网曝门系列| 欧美亚洲日本日韩在线| 免费人成激情视频在线观看冫| 国产精品一卡二卡三卡| 欧美亚洲人成网站在线观看| 国产精品青草久久福利不卡| 在线观看特色大片免费网站| 风韵饥渴少妇在线观看| 波多野无码黑人在线播放| 西西人体大胆午夜视频| 99久久综合狠狠综合久久| 中文字幕在线亚洲日韩6页| 天堂中文在线最新版地址| 日本人妻丰满熟妇久久久久久| 97成人碰碰久久人人超级碰oo| 欧美成人高清视频a在线看| 最新高清无码专区| 西西人体大胆午夜啪啪| 亚洲一线产区二线产区分布| 丰满岳妇乱一区二区三区| 青青国产线免观| 亚洲成国产人片在线观看| 中文字幕无码精品亚洲资源网久久 |