在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. VP40 Antibody

VP40 Antibody

Rare Species
  • 中文名稱：
    VP40兔多克隆抗體
  • 貨號：
    CSB-PA762349HA01ZAT
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: VP40 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 51 kDa
      Observed band size: 51 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Zaire ebolavirus VP40 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    VP40
  • 別名：
    VP40Matrix protein VP40 antibody; Ebola VP40 antibody; eVP40 antibody; Membrane-associated protein VP40 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Zaire ebolavirus
  • 免疫原：
    Recombinant Zaire ebolavirus Matrix protein VP40 protein (1-326AA)
  • 免疫原種屬：
    Zaire ebolavirus
  • 標記方式：
    Non-conjugated

    本頁面中的產品，VP40 Antibody (CSB-PA762349HA01ZAT)，的標記方式是Non-conjugated。對于VP40 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA762349HB01ZAT VP40 Antibody, HRP conjugated ELISA
    FITC CSB-PA762349HC01ZAT VP40 Antibody, FITC conjugated
    Biotin CSB-PA762349HD01ZAT VP40 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD6IP/ALIX, NEDD4 or TGS101. The interaction with host E3 ubiquitin ligase SMURF2 also facilitates virus budding. May play a role in immune cell dysfunction by being packaged into exosomes that can decrease the viability of recipient cells (via RNAi suppression and exosome-bystander apoptosis).
  • 基因功能參考文獻：
    1. Modulation of the VP40-SUMO (SUMOylation) interaction may represent a novel target for the therapy of Ebola virus infection. PMID: 27849047
    2. This VP40 hexamer-hexamer interface is crucial in forming the Ebola viral matrix and disruption of this interface may provide a method to use graphene or similar nanoparticle based solutions as a disinfectant that can significantly reduce the spread of the disease and prevent an Ebola epidemic. PMID: 28917841
    3. Interdomain salt-bridges in the Ebola virus protein VP40 and their role in domain association and plasma membrane localization. PMID: 27328459
    4. Analysis of binding utilizing surface plasmon resonance for several mAbs and sdAb specific for VP40 from Ebola virus. PMID: 28109682
    5. Data indicate that cell penetrable human scFvs (transbodies) to Zaire Ebolavirus (EBOV) VP40 were produced. PMID: 27638305
    6. Taken together, these studies suggest that PM phosphatidylserine may be an important component of Ebola virus budding and that VP40 may be able to mediate PM scission. PMID: 25315776
    7. Results provide a functional model for ebolavirus matrix assembly and the other roles of VP40 in the virus life cycle and demonstrate how a single wild-type, unmodified polypeptide can assemble into different structures for different functions.[Ebola virus Mayinga strain] PMID: 23953110
    8. Host IQGAP1 and Ebola virus VP40 interactions facilitate virus-like particle egress. PMID: 23637409
    9. VP40 membrane penetration is an important step in the plasma membrane localization of the matrix protein where oligomerization and budding are defective in the absence of key hydrophobic interactions with the membrane PMID: 23297401
    10. In addition to viral protein 35 (VP35), we found that VP30 and VP40 independently act as suppressor of RNA silencing. PMID: 21228243
    11. VP40 directly enhances tubulin polymerization without any cellular mediators. PMID: 15795257
    12. enhance our understanding of Ebola virus assembly and in so doing move us closer to the identification of targets for the development of antiviral compounds to combat Ebola virus infection PMID: 17229682
    13. VP40 sequence that may be essential for Ebola virus budding, through the generation of deletion and alanine-scanning mutants. PMID: 17940963
    14. We found that Sec24C, a component of the host COPII vesicular transport system, interacts specifically with VP40 via VP40 amino acids 303 to 307. PMID: 18329616

    顯示更多

    收起更多

  • 亞細胞定位：
    Host cytoplasm. Host cell membrane. Virion membrane; Peripheral membrane protein. Host late endosome membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Host endomembrane system; Peripheral membrane protein. Secreted, extracellular exosome.
  • 蛋白家族：
    Filoviridae matrix protein VP40 family
  • 數據庫鏈接：

    KEGG: vg:911825



主站蜘蛛池模板： 久久无码中文字幕免费影院| 一本大道东京热无码aⅴ| 精品亚洲麻豆1区2区3区| 国产精品极品美女自在线观看免费| 久久伊人色av天堂九九| 亚洲国产天堂久久综合| 中文字幕一二三区波多野结衣 | 久久久久中文伊人久久久| 国内精品久久久久影院优| 99e热久久免费精品首页| 亚洲成a人片在线观看无码专区| 免费观看羞羞视频网站| 国产精品青青在线观看爽香蕉| 亚洲国产成人精品福利| 西西人体大胆扒开下部337卩 | 国产亚洲日韩欧美另类第八页| 亚洲aⅴ综合色区无码一区| 性色高清xxxxx厕所偷窥| 国产精品高潮呻吟av久久黄| 欧美日韩亚洲中文字幕一区二区三区 | 国产成人精品一区二区不卡| av大尺度一区二区三区| 亚洲 中文字幕 日韩 无码| 精品久久久久久亚洲综合网| 永久黄网站免费视频性色| 亚洲精品午夜理伦不卡在线观看| 国产精品亚洲欧美中字| 99久久久无码国产精品9| 亚洲欧美日韩国产成人精品影院 | 中文字幕丝袜精品久久| 中国老熟妇自拍hd发布| 18禁超污无遮挡无码免费游戏| 欧洲成人一区二区三区| 一本色道无码道在线观看| 国产 av 仑乱内谢| 亚洲愉拍二区一区三区| 无码中文字幕日韩专区视频| 男女啪啪做爰高潮免费网站| 成人午夜免费无码区| 国产高清色高清在线观看| 色噜噜狠狠狠狠色综合久|