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VKORC1L1 Antibody, Biotin conjugated

  • 中文名稱:
    VKORC1L1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA818673LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) VKORC1L1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    VKORC1L1
  • 別名:
    VKORC1L1; Vitamin K epoxide reductase complex subunit 1-like protein 1; VKORC1-like protein 1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Vitamin K epoxide reductase complex subunit 1-like protein 1 protein (38-91AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.
  • 基因功能參考文獻:
    1. This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses. PMID: 29054760
    2. a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration PMID: 24532791
    3. VKORC1L1 is responsible for driving vitamin K-mediated intracellular antioxidation pathways critical to cell survival. PMID: 21367861
    4. VKORC1L1 does not affect the variability of warfarin dose requirement in a Japanese patient population PMID: 17996924
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    VKOR family
  • 數據庫鏈接:

    HGNC: 21492

    OMIM: 608838

    KEGG: hsa:154807

    STRING: 9606.ENSP00000353998

    UniGene: Hs.427232



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