在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

VGLL4 Antibody, HRP conjugated

  • 中文名稱:
    VGLL4兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA613487LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) VGLL4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    VGLL4
  • 別名:
    VGLL4 antibody; KIAA0121 antibody; Transcription cofactor vestigial-like protein 4 antibody; Vgl-4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Transcription cofactor vestigial-like protein 4 protein (43-277AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May act as a specific coactivator for the mammalian TEFs.
  • 基因功能參考文獻:
    1. Hippo pathway transcription factor TEAD4 directly associates with the Wnt pathway transcription factor TCF4 via their DNA-binding domains, forming a complex on target genes. VGLL4 binds to this TEAD4-TCF4 complex to inhibit transactivation of both TCF4 and TEAD4. PMID: 28051067
    2. Results identify VGLL4 as a direct target gene of miR-130b in Bladder cancer (BCa) cells. Its suppression is crucial for miR-130b-induced BCa cell proliferation, migration and invasion. PMID: 29512748
    3. The Vgll4 is phosphorylated in vitro and in vivo by cyclin-dependent kinase 1 (CDK1) during antimitotic drug-induced mitotic arrest and also in normal mitosis. PMID: 28739871
    4. VGLL4 - novel candidate genes validated in a large case-control sample of schizophrenia. PMID: 26460480
    5. The expression level of VGLL4 protein was down-regulated in gastric cancer tissues.VGLL4 inhibits epithelial-mesenchymal transition in part through suppressing Wnt-beta-catenin signaling pathway in gastric cancer. PMID: 25701461
    6. our study suggested that downregulation of VGLL4 was very important in the progression of ESCC, and restoring the function of VGLL4 might be a promising therapeutic strategy for ESCC. PMID: 25352025
    7. VGLL4 directly competes with YAP in binding to TEADs and executes its growth-inhibitory function through two TDU domains. PMID: 24458094
    8. rs2616551 in VGLL4 was found to be nominally associated with anorexia nervosa. PMID: 24983835
    9. This study introduces a novel gain-of-function approach for studying hESC maintenance and presents VGLL4 as a previously undescribed regulator of this process. PMID: 23765749
    10. Loss of VGLL4 expression is associated with gastric cancer. PMID: 24525233
    11. Vgl-4 may play a role in the apoptotic pathways by regulating translocation of IAPs between different cell compartments. PMID: 21839727
    12. IRF2BP2 was identifies as a novel VGLL4 partner. PMID: 20702774
    13. Vgl-4 modulates the activity of TEF-1 factors and counteracts alpha1-adrenergic activation of gene expression in cardiac myocytes PMID: 15140898
    14. A transcriptional cofactor of transcriptional enhancer factor-1 (TEF-1) transcription factors. Interacts with TEF-1 factors through 2 TDU (tondu) motifs. Controls gene expression in cardiac myocytes. PMID: 15140898
    15. This gene is named Vestigial-like 4, to distinguish it from 3 previously described genes Vgl-1, Vgl-2 and Vgl-3. Contains 2 motifs, found in the Drosophila transcription cofactor Vestigial, that interact with the TEF-1 family of transcription factors. PMID: 15140898

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Vestigial family
  • 數據庫鏈接:

    HGNC: 28966

    KEGG: hsa:9686

    STRING: 9606.ENSP00000404251

    UniGene: Hs.740389



主站蜘蛛池模板: 一边摸一边抽搐一进一出视频| 欧美一区二区三区啪啪| 免费的黄网站在线观看| 亚洲精品成人片在线观看精品字幕 | 午夜福利18以下勿进免费| 尤物193在线人妻精品免费| 黑人尾随强伦姧人妻爽翻天| 国产熟妇人妻精品一区二区动漫| 久久精品www人人做人人爽| 人妻聚色窝窝人体www一区| 国产suv精品一区二区| 脱岳裙子从后面挺进去在线观看| 国产高清亚洲精品视bt天堂频| 亚洲综合最新无码2020av| 少妇被又大又粗下爽a片| 无码av最新高清无码专区| 2019日韩中文字幕mv| 亚洲国产精品成人久久| 中文字幕一区二区三区日韩精品| 99在线精品一区二区三区| 国产一区精选播放022| 好爽又高潮了毛片免费下载| 五月花成人网| 久久午夜无码鲁丝片秋霞| 同性女女黄h片在线播放| 又色又爽又黄还免费毛片96下载 | 女厕厕露p撒尿八个少妇| 特黄熟妇丰满人妻无码| 无码乱人伦一区二区亚洲一| 最新系列国产专区|亚洲国产| 77777亚洲午夜久久多喷| 蜜臀av 国内精品久久久| 天天摸夜夜添夜夜无码| 人人妻人人狠人人爽| 国产白丝无码免费视频| 免费毛片在线看片免费丝瓜视频 | 18禁止看的免费污网站| 无码人妻精品一区二| 又黄又粗又爽免费观看| av中文无码韩国亚洲色偷偷| 人人妻人人澡人人爽欧美二区|