在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. VEGFB Antibody

VEGFB Antibody

  • 中文名稱：
    VEGFB兔多克隆抗體
  • 貨號：
    CSB-PA004444
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using VEGF-B Polyclonal Antibody
    • Western Blot analysis of COLO 293T HELA cells using VEGF-B Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Vascular endothelial growth factor B antibody; Vascular endothelial growth factor-related factor antibody; VEGF B antibody; VEGF related factor antibody; VEGF-B antibody; VEGF-related factor antibody; Vegfb antibody; VEGFB_HUMAN antibody; VEGFL antibody; VRF antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human VEGF-B.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
  • 基因功能參考文獻：
    1. High plasma VEGF-B levels are associated with type 2 diabetes mellitus. PMID: 28523459
    2. Data from clinical studies point out the changes in circulating or tissue expression levels of VEGF-B in obese compared with lean patients. PMID: 28798193
    3. Cardiac transgenic vascular endothelial growth factor-B overexpression failed to protect heart transplants from ischemia-reperfusion injury. PMID: 27588416
    4. renal VEGF-B expression correlates with the severity of Diabetic Kidney Disease. PMID: 28190774
    5. Data show that metformin treatment reduces serum vascular endothelial growth factor B (VEGF-B) levels and ameliorates insulin resistance. PMID: 26387747
    6. Frameshift mutations of VEGFB gene is associated with stomach and colorectal cancers. PMID: 25633991
    7. fluid shear stress induces the synthesis of Insulin growth factor-2 and vascular endothelial growth factor (VEGF) B and D, which in turn transactivate MMP-12. PMID: 25435370
    8. MMP9 may activate VEGF-B via PI3K/Akt signaling pathway. PMID: 25424698
    9. Roles of vascular endothelial growth factor in amyotrophic lateral sclerosis. PMID: 24987705
    10. Low VEGFB and VEGFD gene expression is associated with early-stage non-small cell lung cancer. PMID: 24145997
    11. Our study suggested that VEGF-B was an angiogenesis factor in vitro and that ERK1/2 and p38-related signaling pathways were involved in these VEGF-B activities. PMID: 24374930
    12. VEGF-B has possible roles in cardiac protection, energy metabolism support, and neuroprotectin [review] PMID: 24987005
    13. High VEGF-B levels might correlate with the presence of hyperlipidemia and target organ damage in type 2 diabetic patients. PMID: 25001655
    14. High VEGFB expression is associated with bone marrow metastasis in neuroblastoma. PMID: 23553333
    15. VEGF-B might be an important ligand in the signalling between the tumor and preexisting blood vessels to ensure a functional blood supply for tumor survival. PMID: 23417498
    16. we report significant associations with overall survival and distant failure for certain VEGF(VEGF-B) family members. PMID: 23728940
    17. Data indicate that three miRs (miR-484, -642, and -217) were able to predict chemoresistance and vasculature of serous epithelial ovarian carcinomas through the regulation of the VEGFB and VEGFR2 pathways. PMID: 23697367
    18. Expression of VEGF-B genes in glioma cell lines U87 is significantly changed under hypoxia and ischemic conditions. PMID: 23350126
    19. In WT1 mutant cells, reduced VEGF(165)b was due to lack of WT1-mediated transcriptional repression of the splicing-factor kinase SRPK1 PMID: 22172722
    20. analysis of binding of vascular endothelial growth factor-B by VEGFR-1(D2) PMID: 20501651
    21. TIMP3 blocks the binding of VEGF to VEGF receptor-2 and inhibits downstream signaling and angiogenesis. PMID: 12652295
    22. Results describe the crystal structure of human vascular endothelial growth factor-B (VEGF-B) and present a predicted model for the association of VEGF-B with the second domain of its receptor, VEGFR-1. PMID: 16616187
    23. Basophils could play a role in angiogenesis and inflammation through the expression of several forms of VEGF-B and their receptors. PMID: 17082651
    24. VEGFB, and receptor were highly expressed in dysplastic neurons. IR in astroglial and balloon cells was observed for VEGFA and its receptors Double-labeling also showed expression of VEGFA, VEGFB and VEGFR-1 in cells of the microglia/macrophage lineage. PMID: 18317782
    25. VEGF-B appears to have a relatively restricted angiogenic activity in the ischemic heart. PMID: 18511699
    26. Increased VEGFB expression is associated with hepatocellular carcinoma PMID: 18537151
    27. Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. PMID: 18757827
    28. The structural features of the 'highly ordered' interaction of the Fab fragment of the antibody (Fab-2H10) with VEGF-B, is presented. PMID: 18930733
    29. VEGF-B mRNA was not expressed either in normal urothelium or in bladder cancer. PMID: 19424629

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
  • 蛋白家族：
    PDGF/VEGF growth factor family
  • 組織特異性：
    Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 12681

    OMIM: 601398

    KEGG: hsa:7423

    STRING: 9606.ENSP00000311127

    UniGene: Hs.732095



主站蜘蛛池模板： 插b内射18免费视频| 天天摸天天摸天天天天看| 一本aⅴ高清一区二区三区| 日韩不卡1卡2卡三卡2021精品推荐| 嫩草av久久伊人妇女超级a| 日日干夜夜干| 中文字幕亚洲制服在线看| 亚洲国产精品无码久久秋霞| 嫩草伊人久久精品少妇av| 色综合中文综合网| 亚洲va中文字幕无码久久 | 色综合久久88色综合天天| 137裸交肉体摄影| 婷婷丁香六月激情综合啪 | 久久97超碰色中文字幕总站| 国产无遮挡裸体免费视频在线观看| 国产大屁股视频免费区| 国产日韩亚洲大尺度高清| 欧美性猛交xxxx乱大交蜜桃| 色一情一乱一伦一区二区三区日本| 亚洲aⅴ无码国精品中文字慕| 国产女人天天春夜夜春| 久久人妻少妇嫩草av| 最近中文字幕mv在线资源| 影音先锋人妻av中文字幕久久 | 国产精华av午夜在线| 欧美黑人疯狂性受xxxxx喷水| 黑人玩弄人妻1区二区| 国产精品va在线观看老妇女| 成人女人看片免费视频放人| 女人裸体性做爰视频| 欧美综合精品久久久久成人影院| 性暴力欧美猛交在线播放| 国产精品无码人妻一区二区在线| 仙踪林果冻传媒一区二区| 人妻无码中文字幕永久在线| 无码国产精品一区二区免费模式 | 高清情侣国语自产拍| a欧美爰片久久毛片a片| 国产乱码一区二区三区| 一区二区三区中文字幕|