在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. VASH2 Antibody

VASH2 Antibody

  • 中文名稱：
    VASH2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA943365
  • 規(guī)格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela and 293T cell, Primary antibody: CSB-PA943365(VASH2 Antibody) at dilution 1/450 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ12505 antibody; OTTHUMP00000035013 antibody; OTTHUMP00000035017 antibody; OTTHUMP00000228345 antibody; OTTHUMP00000228346 antibody; OTTHUMP00000228347 antibody; RP11-275G3.1 antibody; VASH2 antibody; VASH2_HUMAN antibody; Vasohibin-2 antibody; Vasohibin-like protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Full length fusion protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation.
  • 基因功能參考文獻(xiàn)：
    1. VASH2 may promote drug resistance of breast cancer cells through regulating ABCG2 via the AKT signaling pathway. PMID: 29039601
    2. These results suggest that VASH-2 could play an important role in the pathogenesis of renal diseases, and that VASH-2 is closely associated with hypertension and impaired glucose tolerance. PMID: 29042694
    3. VASH1 and VASH2 but not SVBP alone, increased detyrosination of -tubulin, and purified vasohibins removed the C-terminal tyrosine of -tubulin. PMID: 29146869
    4. These results suggest that VASH2 plays an important role in gastric tumor progression via the accumulation of cancer-associated fibroblasts PMID: 28960674
    5. The present study suggests a protective effect of miR-200b/c on high glucose induced human retinal microvascular endothelial cell line dysfunction by inhibiting VASH2. PMID: 28882646
    6. VASH2 expression is positively correlated with FGF2 expression and promotes angiogenesis in human luminal breast cancer by transcriptional activation of fibroblast growth factor 2 through non-paracrine mechanisms. PMID: 27702660
    7. These data suggest that VASH2 reduces the chemosensitivity to gemcitabine in pancreatic cancer cells via JUN-dependent transactivation of RRM2. PMID: 28327155
    8. identified a novel UPS regulatory system in which essential domain architecture (VASH-PS) of VASHs, comprising regions VASH191-180 and VASH280-169 , regulate the cytosolic punctate structure formation in the absence of SVBP. PMID: 27879017
    9. The results indicate that VASH2 played a significant role in the epithelial-mesenchymal transition by modulating the TGF-beta signaling. PMID: 28064471
    10. to the best of our knowledge, these results are the first clinical data indicating that nuclear VASH2, but not cytoplasmic VASH2, promotes cell proliferation by driving the cell cycle from the G0/G1 to S phase. PMID: 26177649
    11. MiR200-upregulated Vasohibin 2 promotes the malignant transformation of tumors by inducing epithelial-mesenchymal transition in hepatocellular carcinoma PMID: 25269476
    12. Suggest that overexpression of VASH2 in pancreatic ductal adenocarcinoma accelerated the pace of tumor development toward a more serious malignant phenotype and was associated with a poor clinical outcome. PMID: 25916042
    13. VASH1 and VASH2 showed distinctive localization and opposing function on the fetoplacental vascularization. PMID: 25184477
    14. VASH2 overexpression downregulated wild-type p53. PMID: 24595063
    15. VASH2 expressed in serous ovarian carcinoma cells promoted tumor growth and peritoneal dissemination by promoting angiogenesis. PMID: 22826464
    16. This is the first study to report differences in the intracellular localization of the VASH2 protein and, hence, a new research direction on the study of VASH2 PMID: 23615928
    17. vasohibin-1 and vasohibin-2 mRNA are expressed in gastric cancer cells and in tumor-associated macrophages (TAMs), and their expressions are altered by hypoxia. PMID: 22438034
    18. VASH2 contributes to the angiogenesis in hepatocellular carcinoma via an Small vasohibin binding protein-mediated paracrine mechanism. PMID: 22614011
    19. Data suggest that VASH1 is expressed in vascular endothelium to terminate angiogenesis; VASH2 appears to be expressed in other cells (primarily mononuclear leukocytes) to promote angiogenesis. [REVIEW] PMID: 23100270

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Secreted. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Vasohibin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 25723

    OMIM: 610471

    KEGG: hsa:79805

    UniGene: Hs.96885



主站蜘蛛池模板： 日日摸日日碰夜夜爽无| 亚洲精品国产av成拍色拍个| 免费观看羞羞视频网站| 波多野结衣中文字幕久久| 丰满多毛的陰户视频| 男人吃奶摸下挵进去好爽| 黑人巨大av无码专区| 欧美成人a在线网站| 亚洲第一区无码专区| 欧美大屁股流白浆xxxx| 日韩美女自卫慰黄网站| 亚洲人精品亚洲人成在线| 人妻无码精品久久亚瑟影视 | 久久人人做人人爽人人av| 国产麻传媒精品国产av| 国产麻花豆剧传媒精品mv在线| 一本久久综合亚洲鲁鲁五月天| 香蕉噜噜噜噜私人影院| 亚洲日本va中文字幕人妖| 202丰满熟女妇大| 亚洲日韩av一区二区三区四区 | 国产美女在线精品免费观看 | 一本大道久久香蕉成人网| 香港三级日本三级韩级人妇| 中文无码vr最新无码av专区| 精品性高朝久久久久久久| 亚洲中文有码字幕日本| 久久99热久久99精品| 免费纯肉3d动漫无码网站| 日本熟妇色高清免费视频| 无码帝国www无码专区色综合 | 国产精品美女久久久网av| 久久精品女人的天堂av| 国产超碰人人做人人爱| 国产猛烈高潮尖叫视频免费| 亚洲国色天香卡2卡3卡4| 亚色九九九全国免费视频| 最近的中文字幕在线看视频| 手机看片福利一区二区三区| 国产精品久久自在自线不卡| 中文无码人妻有码人妻中文字幕|