在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

USP28 Antibody

  • 中文名稱:
    USP28兔多克隆抗體
  • 貨號:
    CSB-PA271019
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA271019(USP28 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthetic peptide of Human USP28
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

相關產品

靶點詳情

  • 功能:
    Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). In contrast, it does not deubiquitinate PLK1. Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBW7) complex. In contrast, it does not interact with isoform 4 of FBXW7 (FBW7gamma) in the nucleolus, allowing MYC degradation and explaining the selective MYC degradation in the nucleolus. Deubiquitinates ZNF304, hence preventing ZNF304 degradation by the proteasome and leading to the activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) in a subset of colorectal cancers (CRC) cells.
  • 亞細胞定位:
    Nucleus, nucleoplasm.
  • 蛋白家族:
    Peptidase C19 family, USP28 subfamily
  • 數據庫鏈接:

    HGNC: 12625

    OMIM: 610748

    KEGG: hsa:57646

    STRING: 9606.ENSP00000003302

    UniGene: Hs.503891



主站蜘蛛池模板: 在线观看无码av网址| 欧美国产日韩a在线观看| 国产成人92精品午夜福利| 国产放荡对白视频在线观看| 无码人妻精品一二三区免费 | 亚洲精品第一国产综合精品| 国语自产精品视频在 视频| 麻豆av久久av盛宴av| 亚洲熟女一区二区三区| 无码高潮又爽又黄a片软件| 久久人妻xunleige无码| 午夜dj在线观看高清在线视频完整版| 精产国品一二三产区m553麻豆 | 美女露出奶头扒开尿口视频直播| 国产欧美亚洲精品a| 69久久精品无码一区二区| 蜜臀av综合网| 国产精品欧美成人| 欧洲精品码一区二区三区免费看| 午夜福利视频合集1000| 欧美人成视频在线视频| 国产精品人妻一区二区高| 精品人妻av区乱码| 一本久道久久综合狠狠躁av| 茄子在线看片免费人成视频| 国产精品久久久久久久久久免费看| 熟女人妻在线视频| 免费h动漫无码网站| 国产精品门事件av| 久久久久无码国产精品不卡| 亚洲人成精品久久久久桥| 亚洲国产成人久久综合一区77| 久久久久久久久久久久久9999| 成人性生交大片免费看96| 在线看片免费人成视频在线影院 | 99热亚洲色精品国产88| 久久精品超碰av无码| 天天摸夜夜摸夜夜狠狠摸| 宅男66lu国产在线观看| 99国产欧美久久久精品| 性生交大片免费看女人按摩 |