在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

USO1 Antibody, Biotin conjugated

  • 中文名稱:
    USO1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA025694LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) USO1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    USO1
  • 別名:
    General vesicular transport factor antibody; General vesicular transport factor p115 antibody; P115 antibody; Protein USO1 homolog antibody; TAP antibody; Transcytosis associated protein antibody; Transcytosis-associated protein antibody; Uso1 antibody; USO1_HUMAN antibody; VDP antibody; Vesicle docking protein antibody; Vesicle docking protein p115 antibody; Vesicle-docking protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human General vesicular transport factor p115 protein (591-733AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.
  • 基因功能參考文獻:
    1. USO1 gene may be a promising target for the therapy of human multiple myeloma and its diagnosis marker. PMID: 26898451
    2. USO1 gene has a critical role in human colon cancer: USO1 is involved in cell proliferation and cell migration of colon cancer cells. PMID: 26184508
    3. P115 promotes proliferation of gastric cancer cells through an interaction with MIF. PMID: 24379579
    4. Scyl1 interacts with 58K/formiminotransferase cyclodeaminase (FTCD) and golgin p115, and is required for the maintenance of Golgi morphology. PMID: 20209057
    5. p115 plays a critical role in mitosis progression, implicating it as the only known golgin to regulate both mitosis and apoptosis PMID: 21536679
    6. a conserved tethering function of the Golgi protein p115 CTF which promotes p53-ERK interaction for the amplification of the apoptotic signal. PMID: 21147777
    7. Data show that the number of tandem ARM repeats in an ARM fold ranges from 6 to 12. PMID: 20126549
    8. Data show that p115 degradation plays a key role in amplifying the apoptotic response independently of Golgi fragmentation. PMID: 12438416
    9. p115 acts directly, rather than via a tether, to catalyze trans-SNARE complex formation preceding membrane fusion. PMID: 14736916
    10. The results suggest that p115 is involved in vesicular transport between endoplasmic reticulum and the Golgi, along with microtubule networks. PMID: 16256943
    11. The interaction between p115 and Cog2 was found to be essential for Golgi ribbon reformation after the disruption of the ribbon by p115 KD or brefeldin A treatment and recovery by re-expression of p115 or drug wash out, respectively. PMID: 17274799
    12. Golgi organization depends on mutually interacting domains in betaCOP and p115, suggesting that vesicle tethering at the Golgi involves p115 binding to the COPI coat PMID: 18434597
    13. nuclear import of the p115 CTF is required for it to stimulate the apoptotic response and suggest that its mode of action is confined to the nucleus. PMID: 19028683
    14. terminal repeat folds into the armadillo superhelical groove and allows homodimeric association with important implications for p115 mediated multiple protein interactions and tethering PMID: 19247479
    15. p115 is a critical intermediary component in the regulated secretion of MIF from monocytes/macrophages PMID: 19454686

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein.
  • 蛋白家族:
    VDP/USO1/EDE1 family
  • 數據庫鏈接:

    HGNC: 30904

    OMIM: 603344

    KEGG: hsa:8615

    UniGene: Hs.744877



主站蜘蛛池模板: 国产欧美国日产高清| 影音先锋人妻av中文字幕久久 | 欧美乱强伦xxxxx高潮| 乱码精品一区二区三区| 国产免费又黄又爽又色毛| 国内少妇毛片视频| 国产午夜鲁丝无码拍拍| 综合精品欧美日韩国产在线| 婷婷伊人五月尤物| 无码人妻精一区二区三区| 又大又粗又爽18禁免费看| 午夜无码一区二区三区在线| 国产午夜永久福利视频在线观看| 日韩欧美在线综合网| 亚洲熟妇色xxxxx欧美老妇| 学生妹无套内射正在播放 | 俺去俺来也www色官网| 亚洲人妻av伦理| 影音先锋男人站| 中文字幕无码精品三级在线电影 | 婷婷五月深爱综合开心网| 国产牛仔裤网站精品| 亚洲爆乳无码专区| 国产av激情久久无码天堂| 国产成人精品a∨一区二区| 欧美疯狂xxxxbbbb喷潮| 色多多性虎精品无码av| 小sao货水好多真紧h无码视频 | 亚洲色欲色欲www成人网| 欧美超级乱婬视频播放| 久久777国产线看观看精品| 久久99亚洲含羞草影院| 自拍偷自拍亚洲精品第1页| 国产乱子夫妻xx黑人xyx真爽| 国产亚洲精品国产福app| 日产精品一卡2卡三卡4乱码| 亚洲国产精品尤物yw在线观看| 国产成人精品白浆久久69| 中文人妻熟妇乱又伦精品| 久久精品国产久精久精| 娇妻玩4p被三个男人伺候电影|