在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UQCRC2 Antibody

  • 中文名稱:
    UQCRC2兔多克隆抗體
  • 貨號:
    CSB-PA923366
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA923366(UQCRC2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA923366(UQCRC2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Mouse muscle tissue and HT-29 cell, A431 and Jurkat cell, Primary antibody: CSB-PA923366(UQCRC2 Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Complex III subunit 2 antibody; Core protein II antibody; Cytochrome b c1 complex subunit 2 mitochondrial antibody; Cytochrome b-c1 complex subunit 2 antibody; EC 1.10.2.2 antibody; MC3DN5 antibody; mitochondrial antibody; QCR2 antibody; QCR2_HUMAN antibody; Ubiquinol cytochrome c reductase complex core protein 2 mitochondrial antibody; Ubiquinol cytochrome c reductase core protein II antibody; Ubiquinol-cytochrome-c reductase complex core protein 2 antibody; UQCR2 antibody; Uqcrc2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human UQCRC2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP) subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties. May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (Probable).
  • 基因功能參考文獻:
    1. These results provided novel insights into the potential role of UQCRC2 in the tumorigenesis and progression of colorectal cancer PMID: 30115536
    2. Down-regulation of UQCRC2 partly reversed the inhibition of invasion/migration ability and chemoresistance in CDH18 overexpressed glioma cell lines. PMID: 30078018
    3. These data indicate that a homozygous missense mutation in UQCRC2 causes moderately impaired CIII function and severely decreased amounts of CIII and supercomplex, which would be the primary molecular pathogenesis in the patients. PMID: 23281071
  • 相關疾病:
    Mitochondrial complex III deficiency, nuclear 5 (MC3DN5)
  • 亞細胞定位:
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族:
    Peptidase M16 family, UQCRC2/QCR2 subfamily
  • 數據庫鏈接:

    HGNC: 12586

    OMIM: 191329

    KEGG: hsa:7385

    STRING: 9606.ENSP00000268379

    UniGene: Hs.528803



主站蜘蛛池模板: 三级视频兔费看| 热99re久久精品国产首页免费 | 十八禁av无码免费网站| 性无码一区二区三区在线观看| 少妇人妻无码专区视频| 88国产精品视频一区二区三区| 色两性网欧美| 欧美性xxxxx极品少妇| 欧美丰满肥婆videos| 亚洲精品一区二区国产精华液| 玩弄丰满少妇人妻视频| 日本黄页网站免费大全| 精品欧洲av无码一区二区| 亚洲小说区图片区另类春色| 国产α片免费观看在线人| 国产成 人 综合 亚洲| 日本不卡一区二区三区| 对白脏话肉麻粗话av| 国产综合精品久久丫| 亚洲kkk4444在线观看| 中文字幕无码日韩中文字幕| 亚洲欧美日韩精品久久| 国产亚洲成av片在线观看| 99久久国产露脸精品| 日韩精品久久久免费观看| 欧美牲交a欧美牲交aⅴ久久| 吃奶呻吟打开双腿做受在线视频| 人妻少妇精品专区性色av| 丁香婷婷六月综合交清| 青青草视频免费观看| 久久无码av三级| 久久久青草青草免费看| 人人爽人人澡人人人妻、百度| 亚洲欧洲日产国无高清码图片| 国产xxxx99真实实拍| 亚洲va欧美va天堂v国产综合| 国产精品亚洲а∨无码播放| 色欲天天婬色婬香视频综合网| 婷婷综合久久中文字幕| 精品无码一区二区三区爱欲九九| 狠狠爱亚洲五月婷婷av|