在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UNC45A Antibody

  • 中文名稱:
    UNC45A兔多克隆抗體
  • 貨號:
    CSB-PA025625GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    UNC45A
  • 別名:
    UNC45A antibody; SMAP1 antibody; Protein unc-45 homolog A antibody; Unc-45A antibody; GCUNC-45 antibody; Smooth muscle cell-associated protein 1 antibody; SMAP-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human UNC45A
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen.
  • 基因功能參考文獻:
    1. Whole-exome sequencing of all affected individuals and their parents identified biallelic mutations in Unc-45 Myosin Chaperone A (UNC45A) as a likely driver for cholestasis, congenital diarrhea, impaired hearing, and bone fragility. PMID: 29429573
    2. UNC-45a promotes generation of contractile actomyosin bundles through synchronized non-muscle myosin II folding and filament-assembly activities. PMID: 29055011
    3. Results provide novel insights into the molecular mechanisms of neurite growth and define UNC-45A as a novel and master regulator of NMII-mediated cellular processes in neurons. PMID: 28356421
    4. UNC-45A is a crucial component in regulating human NK cell cytoskeletal dynamics via promoting the formation of actomyosin complexes. PMID: 26438524
    5. Findings identify a novel centrosomal function for UNC45A and its role in cell proliferation and tumorigenesis. PMID: 25444911
    6. The authors found that UNC-45A is alternatively expressed at the mRNA and protein levels as two isoforms and that the two isoforms differ only by a proline-rich 15-amino-acid sequence near the amino-terminus. PMID: 21802425
    7. GCUNC-45 is a novel modulator of progesterone receptor chaperoning by hsp90. PMID: 16478993
    8. elevated GC UNC-45 protein expression in ovarian carcinoma proliferation and metastasis. PMID: 17872978
    9. GCUNC45 is required for the normal cellular distribution of Hsp90beta, but not Hsp90alpha. PMID: 18285346

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Predominant in the perinuclear region. Little protein in the nucleus.
  • 組織特異性:
    Detected in peripheral blood leukocytes, bone marrow, adrenal gland, trachea, spinal cord, thyroid, lymph node and stomach.
  • 數據庫鏈接:

    HGNC: 30594

    OMIM: 611219

    KEGG: hsa:55898

    STRING: 9606.ENSP00000407487

    UniGene: Hs.389461



主站蜘蛛池模板: 国产99视频精品免费观看9| 国产成人精品a视频| 免费无码不卡视频在线观看| 国产亚洲成av人片在线观看| 久久久久免费看成人影片| 国产巨大爆乳在线观看| 欧美日韩亚洲国产综合乱| 免费观看又色又爽又湿的软件| 亚洲成av人片一区二区三区| 真人性囗交69视频| 俄罗斯美女真人性做爰| 午夜视频无码国产在线观看| 麻豆国产原创视频在线播放| 免费无码又爽又刺激高潮的app| 中文字幕人成无码人妻综合社区| 人妻少妇精品中文字幕av| 国产又爽又黄无码无遮挡在线观看| 欧美精品成人v高清视频| 久久国产高潮流白浆免费观看 | 色婷婷亚洲一区二区三区| 一 级做人爱全视频在线看| 永久免费观看美女裸体的网站| 亚洲精品成人久久电影网| 亚洲精品无码aⅴ中文字幕蜜桃| 国产精品99久久久久久宅男| 国产精品免费一区二区三区四区| 国产成人啪精品视频免费网站软件| 美女又大又黄www免费网站| 色诱视频在线观看| av香港经典三级级 在线| 亚洲人成电影网站色迅雷| 日韩人妻不卡一区二区三区| 东北老女人高潮大叫对白| 99香蕉国产精品偷在线观看| 国产嫖妓一区二区三区无码| 99九九99九九视频精品| 日本xxxx18野外无毒不卡| 亚洲精品无amm毛片| 少妇高清精品毛片在线视频| 日本工口里番无遮█彩色| 黄瓜视频在线观看网址|