在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UNC45A Antibody

  • 中文名稱:
    UNC45A兔多克隆抗體
  • 貨號:
    CSB-PA025625GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    UNC45A
  • 別名:
    UNC45A antibody; SMAP1 antibody; Protein unc-45 homolog A antibody; Unc-45A antibody; GCUNC-45 antibody; Smooth muscle cell-associated protein 1 antibody; SMAP-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human UNC45A
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as co-chaperone for HSP90. Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell. May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen.
  • 基因功能參考文獻:
    1. Whole-exome sequencing of all affected individuals and their parents identified biallelic mutations in Unc-45 Myosin Chaperone A (UNC45A) as a likely driver for cholestasis, congenital diarrhea, impaired hearing, and bone fragility. PMID: 29429573
    2. UNC-45a promotes generation of contractile actomyosin bundles through synchronized non-muscle myosin II folding and filament-assembly activities. PMID: 29055011
    3. Results provide novel insights into the molecular mechanisms of neurite growth and define UNC-45A as a novel and master regulator of NMII-mediated cellular processes in neurons. PMID: 28356421
    4. UNC-45A is a crucial component in regulating human NK cell cytoskeletal dynamics via promoting the formation of actomyosin complexes. PMID: 26438524
    5. Findings identify a novel centrosomal function for UNC45A and its role in cell proliferation and tumorigenesis. PMID: 25444911
    6. The authors found that UNC-45A is alternatively expressed at the mRNA and protein levels as two isoforms and that the two isoforms differ only by a proline-rich 15-amino-acid sequence near the amino-terminus. PMID: 21802425
    7. GCUNC-45 is a novel modulator of progesterone receptor chaperoning by hsp90. PMID: 16478993
    8. elevated GC UNC-45 protein expression in ovarian carcinoma proliferation and metastasis. PMID: 17872978
    9. GCUNC45 is required for the normal cellular distribution of Hsp90beta, but not Hsp90alpha. PMID: 18285346

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Predominant in the perinuclear region. Little protein in the nucleus.
  • 組織特異性:
    Detected in peripheral blood leukocytes, bone marrow, adrenal gland, trachea, spinal cord, thyroid, lymph node and stomach.
  • 數據庫鏈接:

    HGNC: 30594

    OMIM: 611219

    KEGG: hsa:55898

    STRING: 9606.ENSP00000407487

    UniGene: Hs.389461



主站蜘蛛池模板: 18禁裸体女免费观看| 伊人久久精品无码二区麻豆| 久久久久久久人妻无码中文字幕爆| 免费大黄网站在线观| 久久亚洲人成综合网| 亚洲麻豆av成本人无码网站| 男女猛烈激情xx00免费视频| 亚洲熟女综合色一区二区三区 | 国产精品精华液网站| 深夜国产一区二区三区在线看 | 水蜜桃亚洲一二三四在线| 亚洲一区av无码少妇电影| 亚洲大色堂人在线无码| 亚洲精品无码专区在线播放| 亚洲人成中文字幕在线观看| 中文无码成人免费视频在线观看 | 久久综合99re88久久爱| a毛看片免费观看视频| 精品无码成人网站久久久久久| 三级特黄60分钟在线播放| 欧洲熟妇色 欧美| 午夜福利啪啪无遮挡免费| 99c视频色欲在线| 人妻熟女一区| 欧美乱大交xxxxx潮喷| 国产交换配乱婬视频偷网站| 乱人伦中文无码视频| 荫蒂被男人添的好舒服爽免费视频| 99精品国产兔费观看久久| 内射一区二区精品视频在线观看| 日韩精品一区二区三区色欲av | 奇米影视777四色狠狠| 国色天香网www在线观看| 中文字幕一区在线观看视频 | 日本成本人三级在线观看| 色综合天天综合网国产成人网| 艳妇乳肉豪妇荡乳av无码福利| 精品毛片乱码1区2区3区| 黑人巨大av无码专区| 国产精品美女久久久网av| 人妻少妇精品专区性色av|