在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UGT2B10 Antibody

  • 中文名稱:
    UGT2B10兔多克隆抗體
  • 貨號(hào):
    CSB-PA025587ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA025587ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA025587ESR2HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) UGT2B10 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    UGT2B10
  • 別名:
    UGT2B10; UDP-glucuronosyltransferase 2B10; UDPGT 2B10
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human UDP-glucuronosyltransferase 2B10 protein (20-280AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
  • 基因功能參考文獻(xiàn):
    1. UGT2B10 was for the first time identified as an N-glucosidation enzyme. Generated N-glucosides were excreted primarily by the BCRP transporter. PMID: 29691239
    2. A significant contribution of AS in the regulation of UGT2B10 expression in the liver. PMID: 29438977
    3. UGT2B10 activity or genotype should be considered when using cotinine as a tobacco exposure biomarker, particularly in populations such as African American with high frequencies of UGT2B10 nonfunctional variants. PMID: 28264876
    4. Spatial features influence the potency of UGT2B10 inhibition. PMID: 26669329
    5. UGT2B10 variant allele carriers had increased levels of C-oxidation (P = 0.0099)and all pathways should be considered when characterizing the role of nicotine metabolism on smoking behavior and cancer risk. PMID: 25233931
    6. CYP2A6 and UGT2B10 genotype explain 53% of the variance in oral nicotine glucuronidation. They are also significantly associated with undeuterated (D0) nicotine glucuronidation in individuals smoking ad libitum. PMID: 24192532
    7. the substrate specificity of UGT2B10, highlighting its preference for tertiary amines with higher affinities and clearance values than those of UGT1A4 and UGT1A3. PMID: 23611809
    8. UGT2B17 and UGT2B10 play key roles in the glucuronidation of 3HC in the human liver and that functional polymorphisms in UGT2B17 and UGT2B10 are associated with significantly reduced glucuronidation activities against 3HC. PMID: 22228205
    9. Data show that UGT2B10 predicts MD independently of age, hormone therapy and parity. PMID: 20799965
    10. Data suggest that UGTs 2B10 and 2B17 play important roles in the glucuronidation of nicotine and suggest that the UGT2B10 codon 67 SNP and the UGT2B17 gene deletion reduce overall glucuronidation rates of nicotine and its major metabolites in smokers. PMID: 20876810
    11. UGT2B10 genotype influences nicotine metabolism and should be taken into account when characterizing the role of nicotine metabolism on smoking. PMID: 20501767
    12. Nicotine glucuronidation and UGT2B10 is reported. PMID: 17576790
    13. Data suggest that UGT2B10 is the major hepatic enzyme involved in nicotine/cotinine glucuronidation and that the UGT2B10*2 variant reduces nicotine- and cotinine-N-glucuronidation formation and plays a role in nicotine metabolism and elimination. PMID: 17909004
    14. The UGT2B10(67Tyr) variant corresponding to haplotype C is a functional single nucleotide polymorphism that may be responsible for inter individual variation in NNAL-N-glucuronidation activity and may increase susceptibility to smoking-related cancers. PMID: 18300939

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族:
    UDP-glycosyltransferase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 12544

    OMIM: 600070

    KEGG: hsa:7365

    STRING: 9606.ENSP00000265403

    UniGene: Hs.201634



主站蜘蛛池模板: 曰韩无码二三区中文字幕| 国产免费无遮挡吸乳视频| 精品国产欧美一区二区| 少妇下蹲露大唇无遮挡| 超碰曰口干天天种夜夜爽 | 各种少妇正面bbw撒尿| 久激情内射婷内射蜜桃| 51妺嘿嘿午夜福利| 天天爽夜夜爽人人爽从早干到睌 | 黑人大战欲求不满人妻| 国产高清自产拍av在线| 中文字幕人成乱码熟女| 日韩人妻精品一区二区三区视频| 日本牲交大片无遮挡| 亚洲乱亚洲乱妇无码麻豆| 亚洲人成在线观看网站无码| 18黄暴禁片在线观看| 欧美自拍嘿咻内射在线观看| 精品国产杨幂在线观看| 久久国产偷任你爽任你| 色av专区无码影音先锋| 88国产精品视频一区二区三区| 国产精品久久久久久无码| 国产艳妇av在线出轨| 亚洲中文字幕乱码一区| 亚洲色无码专区在线观看| 欧美人与动牲猛交a欧美精品| 久久久久有精品国产麻豆| 成人欧美一区二区三区a片| 色窝窝免费播放视频在线 | 日本无翼乌邪恶大全彩h| 中文字幕中文有码在线| 日本日本乱码伦专区| 在线观看的av网站| 天天爽天天爽天天爽| 一区二区久久久久草草| 亚洲五月色丁香婷婷婷| 欧美成人一区二区三区片免费| 国产免费久久久久久无码 | av无码精品一区二区三区四区 | 国内精品伊人久久久久影院麻豆 |