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UBXN4 Antibody

  • 中文名稱:
    UBXN4兔多克隆抗體
  • 貨號(hào):
    CSB-PA025536GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    UBXN4
  • 別名:
    UBXN4 antibody; KIAA0242 antibody; UBXD2 antibody; UBXDC1 antibody; UBX domain-containing protein 4 antibody; Erasin antibody; UBX domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human UBXN4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
  • 基因功能參考文獻(xiàn):
    1. Erasin/UBXD2 may be involved in endoplasmic-reticulum-associated protein degradation and in Alzheimer's disease. PMID: 16968747
    2. Knockdown of erasin, a platform for p97/VCP and ubiquilin binding, or knockdown of ubiquilin in human cells slowed degradation of two classical endoplasmic reticulum-associated protein degradation substrates. PMID: 19822669
  • 亞細(xì)胞定位:
    Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope.
  • 組織特異性:
    Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14860

    OMIM: 611216

    KEGG: hsa:23190

    STRING: 9606.ENSP00000272638

    UniGene: Hs.591242



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