在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

UBN1 Antibody

  • 中文名稱:
    UBN1兔多克隆抗體
  • 貨號:
    CSB-PA025505GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    UBN1
  • 別名:
    UBN1 antibody; Ubinuclein-1 antibody; HIRA-binding protein antibody; Protein VT4 antibody; Ubiquitously expressed nuclear protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human UBN1-Specific
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.
  • 基因功能參考文獻:
    1. study points to UBN1 as the determinant of H3.3-specific binding and deposition by the HIRA histone chaperone complex. PMID: 26159857
    2. a 184-amino acid region (from amino acids 39 to 223) at the N-terminal region of Ubn-1 was responsible for the interaction with the PDZ2 domain of ZO-1 PMID: 22245583
    3. By a chromatin immunoprecipitation (ChIP) assay, the authors show that Ubn-1 blocks EB1-human herpesvirus 4 DNA interaction. PMID: 21084479
    4. Analyses have revealed that in most cells ubinuclein occurred in the nucleoplasm, but in cells forming tight junctions it is recruited to the plaque structure of the zonula occludens. PMID: 18823282
  • 亞細胞定位:
    Nucleus, nucleoplasm. Nucleus, PML body. Cell junction, tight junction. Note=Localized as a nuclear speckled-like pattern in proliferating primary fibroblasts. Colocalizes with HIRA, PML and SP100 in PML bodies of senescent cells. Colocalizes with TJP1 and CLDN1. Detected along the upper granular cell layer of epidermis. When overexpressed, accumulates in the nucleus in cells showing defective cytokinesis.
  • 蛋白家族:
    Ubinuclein family
  • 組織特異性:
    Ubiquitous. Also expressed in numerous tumors and cancer cell lines.
  • 數據庫鏈接:

    HGNC: 12506

    OMIM: 609771

    KEGG: hsa:29855

    STRING: 9606.ENSP00000262376

    UniGene: Hs.440219



主站蜘蛛池模板: 精品国产精品三级精品av网址| 国产深夜男女无套内射| 天美麻花果冻视频大全英文版 | 强奷妇系列中文字幕| 人人妻人人澡人人爽秒播| 国产产区一二三产区区别在线| 99久久精品国产成人综合| 国产成人8x人网站视频在线观看| 漂亮人妻洗澡被公强 日日躁| 亚洲精品国产精华液| av亚欧洲日产国码无码| 亚洲男人的天堂在线va| 国产人成视频在线观看| 一区二区亚洲精品国产精华液| 亚洲欧美日本久久综合网站| 亚洲中文字幕乱码熟女在线| 日韩欧群交p片内射中文| 女人爽到高潮免费视频大全 | 国产精品_国产精品_k频道| 产精品视频在线观看免费| 人人插人人插人人爽| 久久久天堂国产精品女人| 国产经典三级av在线播放| 亚洲线精品一区二区三区影音先锋 | 中文字幕久久综合伊人| 中文字字幕乱码视频高清| 艳妇荡女欲乱双飞两中年熟妇| 国模无码一区二区三区| 国产高清乱码又大又圆| 久久精品人人做人人综合| 日韩精品久久无码人妻中文字幕| 国模小婕私拍鲜嫩玉门| 精品国产v无码大片在线观看| 国产又色又爽又刺激在线播放| 东北女人毛多水多牲交视频| 欧美乱码伦视频免费| 久久经精品久久精品免费观看| 老太脱裤让老头玩ⅹxxxx| 国产成人综合95精品视频| 99热久久精里都是精品6| 色窝窝无码一区二区三区成人网站|