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  4. UBE2F Antibody

UBE2F Antibody

  • 中文名稱：
    UBE2F兔多克隆抗體
  • 貨號：
    CSB-PA850248ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA850248ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) UBE2F Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    NCE2 antibody; NEDD8 carrier protein UBE2F antibody; NEDD8 conjugating enzyme antibody; NEDD8 conjugating enzyme UBE2F antibody; NEDD8 protein ligase UBE2F antibody; NEDD8-conjugating enzyme 2 antibody; NEDD8-conjugating enzyme UBE2F antibody; ube2f antibody; UBE2F_HUMAN antibody; Ubiquitin conjugating enzyme E2F antibody; Ubiquitin conjugating enzyme E2F (putative) antibody; Ubiquitin-conjugating enzyme E2 F antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human NEDD8-conjugating enzyme UBE2F protein (1-185AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
  • 基因功能參考文獻：
    1. By ubiquitylating and degrading NOXA through activating CRL5, UBE2F selectively promotes lung cancer cell survival and could, therefore, serve as a novel cancer target PMID: 27591266
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family, UBE2F subfamily
  • 組織特異性：
    Widely expressed (at protein level).
  • 數據庫鏈接：

    HGNC: 12480

    OMIM: 617700

    KEGG: hsa:140739

    STRING: 9606.ENSP00000272930

    UniGene: Hs.471785



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